[HTML][HTML] Predictors of response, progression-free survival, and overall survival in patients with lung cancer treated with immune checkpoint inhibitors

RM Memmott, AR Wolfe, DP Carbone… - Journal of Thoracic …, 2021 - Elsevier
lung cancer. Studies have revealed improved objective response rates, progression-free
survival, and overall survival … subset of unselected patients with lung cancer responds to these …

[HTML][HTML] … overall survival and final progression-free survival data for patients with treatment-naive advanced ALK-positive non-small-cell lung cancer in the ALEX study

T Mok, DR Camidge, SM Gadgeel, R Rosell… - Annals of oncology, 2020 - Elsevier
survival (PFS) with alectinib versus crizotinib in treatment-naive ALK-positive non-small-cell
lung cancer (… We report mature PFS (cut-off: 30 November 2018) and overall survival (OS) …

Five-year overall survival for patients with advanced non‒small-cell lung cancer treated with pembrolizumab: results from the phase I KEYNOTE-001 study

EB Garon, MD Hellmann, NA Rizvi… - Journal of Clinical …, 2019 - ascopubs.org
Overall survival (OS) and duration of response were secondary end points. … For patients
with non‒small-cell lung cancer (NSCLC), median overall survival (OS) and 5-year survival

Impact of EGFR inhibitor in non–small cell lung cancer on progression-free and overall survival: a meta-analysis

CK Lee, C Brown, RJ Gralla, V Hirsh… - … the National Cancer …, 2013 - academic.oup.com
survival and may be important in the development and progression of non–small cell lung
cancer … TKIs) on progression-free survival (PFS) and overall survival (OS) in advanced NSCLC …

Overall response rate, progression-free survival, and overall survival with targeted and standard therapies in advanced non–small-cell lung cancer: US Food and Drug …

GM Blumenthal, SW Karuri, H Zhang… - Journal of Clinical …, 2015 - ascopubs.org
… classification and treatment of lung cancer. Traditionally, lung cancer had been classified
based on histology. With the evolution of technologies to sequence the cancer genome and an …

Overall survival (OS) in patients (pts) with advanced non-small cell lung cancer (NSCLC) harboring common (Del19/L858R) epidermal growth factor receptor …

JCH Yang, LV Sequist, MH Schuler, T Mok… - 2014 - ascopubs.org
8004^ Background: Afatinib (A) is an oral, irreversible ErbB family blocker of EGFR, HER2,
ErbB3 and ErbB4 signalling. LL3 compared A with cisplatin/pemetrexed in 345 pts recruited …

[HTML][HTML] Quitting smoking at or around diagnosis improves the overall survival of lung cancer patients: a systematic review and meta-analysis

S Caini, M Del Riccio, V Vettori, V Scotti… - Journal of Thoracic …, 2022 - Elsevier
Introduction Lung cancer (LC) remains a disease with poor prognosis despite recent advances
in treatments. Here, we aimed at summarizing the current scientific evidence on whether …

Surrogate endpoints for overall survival in chemotherapy and radiotherapy trials in operable and locally advanced lung cancer: a re-analysis of meta-analyses of …

A Mauguen, JP Pignon, S Burdett, C Domerg… - The lancet …, 2013 - thelancet.com
… of chemotherapy and radiotherapy for lung cancer is overall survival. Although reliable and
… We assessed the correlations between potential surrogate endpoints and overall survival at …

[HTML][HTML] Afatinib versus gefitinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: overall survival data from the phase IIb LUX-Lung 7 trial

L Paz-Ares, EH Tan, K O'Byrne, L Zhang, V Hirsh… - Annals of …, 2017 - Elsevier
… blocker, afatinib, significantly improved progression-free survival (PFS), time-to-treatment …
lung cancer (NSCLC). Here, we present primary analysis of mature overall survival (OS) data. …

[HTML][HTML] A validated prediction model for overall survival from stage III non-small cell lung cancer: toward survival prediction for individual patients

C Oberije, D De Ruysscher, R Houben… - International Journal of …, 2015 - Elsevier
… In addition, more accurate prediction of survival would allow … and predictive factors for lung
cancer survival. By contrast, … and validate a prediction model for survival of stage III NSCLC …