… Cell-based therapies that involve transplantation into the striatum of dopaminergic cells have attracted considerable interest as possible treatments for Parkinson'sdisease (PD). …
KC Sonntag, B Song, N Lee, JH Jung, Y Cha… - Progress in …, 2018 - Elsevier
Parkinson'sdisease (PD) is one of the most common neurodegenerative disorders, which affects about 0.3% of the general population. As the population in the developed world ages, …
AO Pires, FG Teixeira, B Mendes-Pinheiro… - Progress in …, 2017 - Elsevier
Parkinson'sdisease (PD) is a neurodegenerative disorder characterized by the degeneration of dopaminergic neurons and/or loss od neuronal projections, in several dopaminergic …
… with Parkinson'sdisease in the early stages of the disease. However, once the “honeymoon” period has waned, usually after a few years of dopaminergic therapy… in Parkinson'sdisease. …
… Pathophysiology of Parkinsondisease: Factors influencing the development of … of novel therapeutic approaches and challenges associated with the current anti-Parkinson drug therapy …
… In summary, a therapeutic intervention aimed at treating Parkinson'sdisease optimally could have an effect lasting years, and be targeted to the nigrostriatal pathway, either through …
RA Barker - Expert Opinion on Pharmacotherapy, 2000 - Taylor & Francis
Parkinson’s disease (PD) is an incurable neurodegenerative condition of the central nervous … This approach has now entered clinical trials and this review will analyse the therapeutic …
S Sarkar, J Raymick, S Imam - International journal of molecular sciences, 2016 - mdpi.com
… while also reducing parkinsonian motor signs. To date, although several anti parkinsonian therapeutics showed promise in providing neuroprotective therapy against this devastating …
… A variety of sources of dopaminergic cells have been investigated for treating PD in this way, and in this review we discuss the basis of these, as well as their prospects for use in clinical …