JD Elsworth - Journal of neural transmission, 2020 - Springer
… treatments for Parkinson’s disease patients are reviewed, which form the foundation for an evaluation of future options to control symptoms and halt progression of the disease. These …
R Ambasudhan, N Dolatabadi, A Nutter… - Journal of …, 2014 - Wiley Online Library
… This study raises the exciting prospect of clinical translation of these approaches if acceptable levels of efficacy and toxicity can be established. Interestingly, robust outgrowth of fibers …
CG Goetz - Cold Spring Harbor perspectives in …, 2011 - perspectivesinmedicine.cshlp.org
… internationally about Parkinson'sdisease. He separated Parkinson'sdisease from multiple sclerosis … Early treatments of Parkinson'sdisease were based on empirical observation, and …
… Parkinson'sdisease (PD) involves motor symptoms reflecting the progressive degeneration of dopaminergic neurons in the substantia nigra. However, diagnosis is only enabled late in …
… Deterioration of mitochondrial functions has been widely reported in normal aging as well as in a spectrum of age-associated neurological diseases, including Parkinson’s disease (PD)…
… well as new and prospective therapies for the disease. The current data suggest that prevention or early treatment of PD may be the most effective therapeutic strategy. New advances in …
K Marek - From Neuroscience To Neurology, 2005 - Elsevier
… Parkinson'sdisease (PD) is a progressive neurodegenerative disorder resulting in severe disability for people with the disease, unrelenting hardship for family members and caregivers, …
… , and assess the prospects for disease modification. Surgical therapies are not considered. … 23 showed the use of levodopa increased Unified ParkinsonDisease Rating Scale (UPDRS) …
P Chopade, N Chopade, Z Zhao… - Bioengineering & …, 2023 - Wiley Online Library
… current clinically approved therapies. To gain a … therapies, and Section 7 discusses novel preclinical strategies. Finally, we conclude the article in Section 8 detailing the future prospects …