, … for Neurodegenerative Diseases Study Group of … - Parkinsonism & related …, 2008 - Elsevier
Nanotechnology will play a key role in developing new diagnostic and therapeutic tools. … All of them are relevant to improve current therapy of Parkinson'sdisease (PD). …
H Vilaça-Faria, AJ Salgado, FG Teixeira - Cells, 2019 - mdpi.com
… Described by James Parkinson in 1817, Parkinson’s disease (PD) is the second most common chronic neurodegenerative disease in the world, affecting over 10 million people, and …
R Cacabelos - International journal of molecular sciences, 2017 - mdpi.com
… From a therapeutic perspective, the introduction of levodopa (l-DOPA) in the 1960s … it continues to be the most effective symptomatic therapy in Parkinsonian disorders [15]. However, the …
… However, Parkinson'sdisease involves degeneration of non-dopaminergic … for Parkinson's disease, and also for the motor complications that arise from the use of existing therapies. …
B Tong, Y Ba, Z Li, C Yang, K Su, H Qi, D Zhang… - … of Disease, 2024 - Elsevier
… of Alzheimer's disease and Parkinson'sdisease and demonstrates the potential of developing relevant therapeutic strategies based on lipid metabolism as a breakthrough point. …
Parkinson’s disease (PD) is a slow insidious neurological disorder characterized by a loss of dopaminergic neurons in the midbrain. Although several recent preclinical advances have …
M Parmar, S Grealish, C Henchcliffe - Nature Reviews Neuroscience, 2020 - nature.com
… replacement therapies have long been an attractive prospect for treating Parkinsondisease. … -derived cell transplants in individuals with Parkinsondisease have been variable, in part …
R Wijeyekoon, RA Barker - … Acta (BBA)-Molecular Basis of Disease, 2009 - Elsevier
Parkinson'sdisease (PD) is a progressive neurodegenerative disorder in which the degeneration of dopaminergic neurons projecting from the substantia nigra to the striatum is a key …
PA LeWitt, S Fahn - Neurology, 2016 - AAN Enterprises
… Although levodopa is widely recognized as the most effective therapy for Parkinsondisease (PD), its introduction 5 decades ago was preceded by several years of uncertainty and …