Stem cells for modeling and therapy of Parkinson's disease

Q Zhang, W Chen, S Tan, T Lin - Human gene therapy, 2017 - liebertpub.com
… embryonic stem cells, human neural stem cells, human-induced pluripotent stem cells,
and … essential pathological processes and charactering single-cell changes in vitro. Furthermore, …

Clinical application of stem cell therapy in Parkinson's disease

M Politis, O Lindvall - BMC medicine, 2012 - Springer
… of stem cells for therapy in Parkinson's disease. 1) Neural stem cells (NSCs) from human
fetal brain, expanded and differentiated to DA-ergic neurons; 2) Pluripotent cells generated …

Stem cells for cell therapy in Parkinson's disease

O Lindvall - Pharmacological research, 2003 - Elsevier
… before stem cell-based therapies can … stem cells of four different sources: embryonic stem
cells from the fertilized egg, neural stem cells from the embryonic or adult brain, or from stem

Stem cells may reshape the prospect of Parkinson's disease therapy

KC Sonntag, R Simantov, O Isacson - Molecular Brain Research, 2005 - Elsevier
… has entered several disease entities including neurodegenerative disorders. Recent
clinical … DA) cells into the brain of Parkinson's disease (PD) patients can reduce disease-associated …

Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease

O Lindvall, Z Kokaia - Trends in Pharmacological sciences, 2009 - cell.com
… development of stem-cell-based approaches. We also describe how far stem cells have got
… the major scientific and clinical problems to be solved for the successful application of stem

Stem cell therapy for Parkinson's disease: safety and modeling

T Stoddard-Bennett, RR Pera - Neural Regeneration Research, 2020 - journals.lww.com
… ’s disease symptoms in mouse and primate models. Here we discuss the history and implications
for cell therapy for Parkinson’s disease, … or halt the progression of Parkinson’s disease. …

Stem cells in the treatment of Parkinson's disease

E Arenas - Brain research bulletin, 2002 - Elsevier
… of novel cell replacement strategies based on the grafting of neural stem cells, and these
will be discussed here. In this review I will also focus on the use of neural stem cells to deliver …

Replacing what's lost: a new era of stem cell therapy for Parkinson's disease

Y Fan, Winanto, SY Ng - Translational Neurodegeneration, 2020 - Springer
… the vast obstacles that stem cell scientists have just begun to … using stem cell-derived products
for cell replacement therapy, … of stem cell therapy, focusing on Parkinson’s disease (PD). …

Novel approach to stem cell therapy in Parkinson's disease

I Garitaonandia, R Gonzalez, G Sherman… - Stem Cells and …, 2018 - liebertpub.com
Stem Cell Corporation’s (ISCO’s) approach to developing a pluripotent stem cell based treatment
for Parkinson’s disease (PD). … study of a pluripotent stem cell based therapy for PD. The …

Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease

HJ Park, PH Lee, OY Bang, G Lee… - Journal of …, 2008 - Wiley Online Library
Parkinson’s disease is a common progressive neurodegenerative disorder caused by the
… We investigated whether cell therapy with human mesenchymal stem cells (hMSCs) had a …