Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease

SH Barage, KD Sonawane - Neuropeptides, 2015 - Elsevier
… Various therapeutic approaches are being used to improve the cholinergic neurotransmission,
but their role in AD pathogenesis is still unknown. Although, an increase in tau protein …

From pathogenesis to therapy–perspective on treatment strategies in fibrotic diseases

A Ramming, C Dees, JHW Distler - Pharmacological research, 2015 - Elsevier
… Indeed, our understanding of the molecular pathogenesis of fibrotic diseases is increasing
and the list of potential molecular targets for the treatment of fibrosis is growing (Table 1). …

Inflammatory bone loss: pathogenesis and therapeutic intervention

K Redlich, JS Smolen - Nature reviews Drug discovery, 2012 - nature.com
… We also discuss the therapeutic potential and limitations of agents that may be used to
treat osteoporosis in chronic inflammatory diseases, as well as novel approaches that are …

Pathogenesis, emerging therapeutic targets and treatment in sialidosis

A d'Azzo, E Machado, I Annunziata - Expert opinion on orphan …, 2015 - Taylor & Francis
Therapy for sialidosis Enzyme replacement therapy (ERT) is the canonical therapeutic
approach for the treatment of non-neuropathic patients with lysosomal storage disorders Citation[…

Salmonella: from Pathogenesis to Therapeutics

EC Boyle, JL Bishop, GA Grassl… - Journal of bacteriology, 2007 - Am Soc Microbiol
… He embodied the spirit of the conference “from pathogenesis to therapeutics,” as his life with
… and pathogenic mechanisms to translating this research into therapeutic approaches and …

Inflammatory bowel disease: pathogenesis, diagnosis and current therapeutic approach

A Silaghi, VD Constantin, B Socea… - Journal of Mind and …, 2022 - scholar.valpo.edu
Inflammatory bowel disease is a group of conditions of unknown etiology, represented by
Crohn’s disease and ulcerative colitis and characterized by the presence of intestinal wall …

[PDF][PDF] Psoriatic arthritis: current concepts on pathogenesis‐oriented therapeutic options

AM Turkiewicz, LW Moreland - Arthritis & Rheumatism, 2007 - Citeseer
… Recent insights into the immunopathogenic mechanisms of PsA have revealed disease
characteristics in the synovium, vascular structures, entheses, and bone of PsA patients that are …

Clinical presentations, pathogenesis, and therapy of sarcoidosis: state of the art

F Polverino, E Balestro, P Spagnolo - Journal of clinical medicine, 2020 - mdpi.com
… features of sarcoidosis, and the current therapeutic approaches used to treat the disease. …
in order to shed light on the possible therapeutic approaches for this multifaceted disease. …

Bronchiectasis—new therapeutic approaches based on pathogenesis

RA Stockley - Clinics in chest medicine, 1987 - Elsevier
therapy can have dramatic effects. Most of this article deals with this concept and the
evidence to support it, as well as a recent therapeutic approach and future potential approaches

Pathogenesis of cholestatic liver disease and therapeutic approaches

GM Hirschfield, EJ Heathcote, ME Gershwin - Gastroenterology, 2010 - Elsevier
… They have common clinical manifestations and pathogenic features that include the … in the
pathogenesis of disease. These discoveries will hopefully lead to new therapeutic approaches