Is a “cytokine storm” relevant to COVID-19?

P Sinha, MA Matthay, CS Calfee - JAMA internal medicine, 2020 - jamanetwork.com
… The actual composition of the cytokine storm at any point in time will show patient-to-patient
We believe that it is premature at this early stage to discount CSS in the pathogenesis of …

Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
… release after treatment causes adverse effects on patient health. The massive release of … to
an unchecked inflammatory cytokine storm is responsible for pathogenesis of many diseases (…

[HTML][HTML] Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
… , in particular, the cytokine storm represent a centerpiece of COVID-19 pathogenesis, causing
… coronavirus infection leads to an inflammatory cytokine storm in the affected patients. The …

The cytokine storm of COVID-19: a spotlight on prevention and protection

L Pearce, SM Davidson, DM Yellon - Expert Opinion on …, 2020 - Taylor & Francis
… released by the immune system in response to pathogenic material ( Figure 1 ). The … In
a study of 133 hematology patients receiving CAR-T, levels of both IL-6 and MCP-1 peaked …

[HTML][HTML] Cytokine storm: the primary determinant for the pathophysiological evolution of COVID-19 deterioration

R Chen, Z Lan, J Ye, L Pang, Y Liu, W Wu… - Frontiers in …, 2021 - frontiersin.org
… the cytokine storm, and accelerates the deterioration of patients to … dysfunction, eventually
leading to the death of patients (3). … The pathogenesis of COVID-19 involves multiple cytokine

[HTML][HTML] Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
cytokines could contribute to the pathogenesis of cerebral malaria [130]. … IL-6 in patients
with COVID-19 were about 12 times lower than in ARDS, about 27 times lower than in patients

Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
pathogenesis of progressive hypoxia in patients with COVID-19. While the initial results with
immune modulators are promising, the results of ongoing clinical trials will clarify the efficacy…

[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
cytokine storm. In this review, we referred COVID-19 associated cytokine storm as the patients
… an increase in the number of pathogenic inflammatory monocyte–macrophages (IMMs) (…

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
pathogenic hCOV infection, a violent cytokine storm causing immune pathological damage
may be a real “killer” in critically ill patientspathogenic mechanism of inflammatory cytokines, …

COVID-19-associated cytokine storm syndrome and diagnostic principles: an old and new Issue

X Yongzhi - Emerging microbes & infections, 2021 - Taylor & Francis
… -19 patients experience sudden and rapid deterioration with the onset of fatal cytokine storm
… of which are caused by infections with pathogenic microorganisms. fHLH/pHLH was also …