Cytokine storm signature in patients with moderate and severe COVID-19

O Kalinina, A Golovkin, E Zaikova, A Aquino… - International Journal of …, 2022 - mdpi.com
… These results indicated a serious immune disorder that previously was reported in other
pathogenic coronaviruses, including Middle East respiratory syndrome coronavirus (MERS) [20] …

Cytokine storm in COVID-19: An overview, mechanism, treatment strategies, and stem cell therapy perspective

NU Azmi, MU Puteri, D Lukmanto - … Sciences and Research, 2020 - scholarhub.ui.ac.id
… in critically ill patients infected SARS-CoV-2. Thus, a better understanding of cytokine
storm-related COVID-19 pathogenesis supports the development of clinical management therapy. …

Cytokine storm and signaling pathways: pathogenesis of SARS‐CoV‐2 infection, managing and treatment strategies

R Kumar, K Gulia - 2021 - wlv.openrepository.com
… for the initiation of severe and deteriorated conditions of lungs which are inter-related to
the emergence of cytokine storm in patient’s bodies. Here, the authors underlined the …

COVID-19 infection: an overview on cytokine storm and related interventions

S Montazersaheb, SM Hosseiniyan Khatibi, MS Hejazi… - Virology journal, 2022 - Springer
… , in which inflammatory cytokines are rapidly secreted in a … cytokine storm is a severe status
observed in patients requiring … In these patients, the aberrant pathogenic T cells secrete …

Targeting the “cytokine storm” for therapeutic benefit

RV D'Elia, K Harrison, PC Oyston… - Clinical and Vaccine …, 2013 - Am Soc Microbiol
… , other pathogenic organisms are capable of hyperstimulating the immune system, commonly
known as a cytokine storm. … of cytokine storms in disease is only just becoming apparent. …

Cytokine drizzle—the rationale for abandoning “cytokine storm

AE Stolarski, J Kim, Q Zhang, DG Remick - Shock, 2021 - journals.lww.com
… “Cytokine storm” has been used to implicate increased cytokine levels in the pathogenesis of
… mainstay of treatment in patients with RA, patients who express IL-6 levels similar to SARS …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
cytokines and pathways implicated in the pathogenesis of COVID-19-associated … cytokine
storm pathophysiology. Elevated levels of IL-6 may lead to multi-organ dysfunction in patients

… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… The functionality of the immune protein is best seen in the pathogenesis of severe viral,
bacterial, and parasitic diseases and cancer. Abnormal production of the proteins is a major …

Quantification of cytokine storms during virus infections

S Yuan, SC Jiang, ZW Zhang, YF Fu, J Hu… - Frontiers in …, 2021 - frontiersin.org
pathogenic virus infections usually trigger cytokine storms, which may have adverse effects
on vital organs and result in high mortalities. The two cytokines … ), and SARS patients showed …

The cytokine storm in COVID-19: Further advances in our understanding the role of specific chemokines involved

F Coperchini, L Chiovato, G Ricci, L Croce… - Cytokine & Growth …, 2021 - Elsevier
… the “cytokine storm”, the event occurring in those patients in … involved in the pathogenesis
of the cytokine storm, potentially … SARS-COV-2 infection-related cytokine storm and how their …