Plcγ2/Tmem178 dependent pathway in myeloid cells modulates the pathogenesis of cytokine storm syndrome

S Mahajan, CE Decker, Z Yang, D Veis, ED Mellins… - Journal of …, 2019 - Elsevier
… This work provides the basis to evaluate the Plcγ2/Tmem178 axis in patients with sJIA to
predict which subset of patients are more likely to develop CSS and underscore the potential …

The triumvirate of NF-κB, inflammation and cytokine storm in COVID-19

A Attiq, LJ Yao, S Afzal, MA Khan - International immunopharmacology, 2021 - Elsevier
… 19 patients. Hence, this review highlights the activation, signal transduction and cross-talk of
NF-κB with regard to cytokine storm … a significant role in the pathogenesis in a majority of the …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - … pathogenesis, 2021 - Elsevier
… that a subgroup of patients with severe COVID-19 might have a cytokine release syndrome.
Such patients have high levels of pro-inflammatory cytokines and chemokines that are …

Brain dysfunction in COVID‐19 and CAR‐T therapy: cytokine storm‐associated encephalopathy

U Pensato, L Muccioli, I Cani, D Janigro… - Annals of Clinical …, 2021 - Wiley Online Library
… , 1 associated in a subgroup of patients with cytokine storm, an acute systemic inflammatory
… as the main pathogenic mechanism, 87, 88 even though CSF cytokine levels have not been…

[PDF][PDF] Cytokine storm syndrome in COVID-19: diagnosis and management strategies

S Maggo, P Dhull, AP Dubey, D Brashier… - Int J Health Sci …, 2020 - researchgate.net
… is called as “cytokine storm syndrome”. It is prudent to diagnose cytokine storm early in the
patients: Implications for pathogenesis virus transmission pathways. J Pathol 2004; 203: 622…

The interplay between inflammatory pathways and COVID-19: A critical review on pathogenesis and therapeutic options

S Choudhary, K Sharma, O Silakari - Microbial pathogenesis, 2021 - Elsevier
… pathways get activated and lead to cytokine storm or cytokine storm syndrome (CSS) [18].
All … in the progression of the cytokine storm in COVID-19 patients, for instance, dysfunction of …

Pathogenesis of macrophage activation syndrome and potential for cytokine-directed therapies

GS Schulert, AA Grom - Annual review of medicine, 2015 - annualreviews.org
pathogenesis is a cytokine storm, with markedly increased levels of numerous proinflammatory
cytokines including IL-1, IL-6… be central to the pathogenesis of MAS in patients with SJIA. …

[HTML][HTML] Impact of cytokine storm and systemic inflammation on liver impairment patients infected by SARS-CoV-2: Prospective therapeutic challenges

FEM Ali, ZM Mohammedsaleh, MM Ali… - World Journal of …, 2021 - ncbi.nlm.nih.gov
… We provide detailed information about the recent mechanisms of COVID-19 pathogenesis,
implications on several hepatic disorders, and potential therapeutic strategies. …

[HTML][HTML] Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major …

P Frisoni, M Neri, S D'Errico, L Alfieri… - … Science, Medicine and …, 2022 - Springer
… The mechanisms underlying the pathogenesis of SARS-CoV-2 in patients with cardiovascular
… players in the multifactorial pathogenesis of COVID-19-associated coagulopathy [61]. …

[HTML][HTML] COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
… It has been shown that aberrant pathogenic T cells and inflammatory monocytes are rapidly
… The authors suggest that the PLR of patients could be a proxy of the cytokine storm, since …