The pathogenesis of pulmonary fibrosis: a moving target

WA Wuyts, C Agostini, KM Antoniou… - European …, 2013 - Eur Respiratory Soc
Pulmonary fibrosis is the end stage of many diffuse parenchymal lung diseases. It is
characterised by excessive matrix formation leading to destruction of the normal lung architecture …

Pathogenesis of idiopathic pulmonary fibrosis

PJ Wolters, HR Collard, KD Jones - Annual Review of Pathology …, 2014 - annualreviews.org
… , a disease of premature aging, develop pulmonary fibrosis provided the first clue that mutations
in age-related genes may predispose to pulmonary fibrosis (20, 32). This association led …

[HTML][HTML] Pulmonary fibrosis: pathogenesis, etiology and regulation

MS Wilson, TA Wynn - Mucosal immunology, 2009 - Elsevier
… The etiology of pulmonary fibrotic diseases is … pulmonary fibrotic conditions, idiopathic
pulmonary fibrosis (IPF), is still unclear. This review examines common mechanisms of pulmonary

[HTML][HTML] Idiopathic pulmonary fibrosis: pathogenesis and management

G Sgalla, B Iovene, M Calvello, M Ori, F Varone… - Respiratory …, 2018 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive disease characterized
by the aberrant accumulation of fibrotic tissue in the lungs parenchyma, associated with …

[HTML][HTML] Role of interleukins in the pathogenesis of pulmonary fibrosis

YX She, QY Yu, XX Tang - Cell Death Discovery, 2021 - nature.com
pulmonary fibrosis. In this article, we reviewed the relationship between interleukins and
pulmonary fibrosis … -targeted treatment on experimental pulmonary fibrosis, clinical applications …

[HTML][HTML] Why do patients get idiopathic pulmonary fibrosis? Current concepts in the pathogenesis of pulmonary fibrosis

PS Bellaye, M Kolb - BMC medicine, 2015 - Springer
… Idiopathic pulmonary fibrosis (IPF… pathogenesis it is likely that complex relationships between
genetic predispositions, environmental exposures, and lung infections promote the fibrotic

Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis

KC Meyer - Expert review of respiratory medicine, 2017 - Taylor & Francis
… , pathogenesis, and diagnosis of pulmonary fibrosis with an … with risk of developing pulmonary
fibrosis, and an improved … in the development of pulmonary fibrosis is rapidly evolving. …

Idiopathic pulmonary fibrosis: pathogenesis and therapeutic approaches

M Selman, VJ Thannickal, A Pardo, DA Zisman… - Drugs, 2004 - Springer
pathogenesis of IPF has not been elucidated, early concepts focused on lung injury leading
to a cycle of chronic alveolar inflammation eventuating in fibrosis … in the pathogenesis of IPF, …

[HTML][HTML] Pathogenic mechanisms underlying idiopathic pulmonary fibrosis

BJ Moss, SW Ryter, IO Rosas - Annual Review of Pathology …, 2022 - annualreviews.org
… been associated with pathogenic mechanisms such as … pathogenesis, most described
genetic variations are neither necessary nor sufficient for the development of pulmonary fibrosis

Idiopathic pulmonary fibrosis: new insights into pathogenesis

PW Noble, RJ Homer - Clinics in chest medicine, 2004 - chestmed.theclinics.com
Despite improvements in the diagnostic approach to idiopathic pulmonary fibrosis (IPF) in
recent years, the pathogenesis remains poorly understood. IPF is a clinical, physiologic, …