… of elevated levels of pro‐inflammatory cytokines in SARS‐CoV‐infected ACE2+ cells in SARS patients: relation to the acute lung injury and pathogenesis of SARS

L He, Y Ding, Q Zhang, X Che, Y He… - The Journal of …, 2006 - Wiley Online Library
… the expression of pro-inflammatory cytokines (PICs), which may play a role in the pathogenesis
of SARS 20, 21. However, it is unclear whether SARS-CoV infection induces increased …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - … pathogenesis, 2021 - Elsevier
… It results from the release by immune and non-immune effector cells of substantial
amounts of pro-inflammatory cytokines and appears to contribute to SARS-CoV-2 pulmonary …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
… Here, we explore the involvement of chemokines in the pathogenesis of COVID-19, which
helps to understand the pathology better and discover potential novel treatment targets. …

COVID-19: Pathogenesis, cytokine storm and therapeutic potential of interferons

SH Nile, A Nile, J Qiu, L Li, X Jia, G Kai - Cytokine & growth factor reviews, 2020 - Elsevier
… to control SARS-CoV2 hyperinflammation and cytokine storm, … cytokine storm - an uncontrolled
systemic inflammatory response resulting from the release of pro-inflammatory cytokines

SARS coronavirus pathogenesis: host innate immune responses and viral antagonism of interferon

AL Totura, RS Baric - Current opinion in virology, 2012 - Elsevier
… ARDS is also associated with the induction of inflammatory cytokines including IL-1, IL-6,
IL-8, CXCL-10, and TNFα, many of which were highly expressed in the lungs of …

[PDF][PDF] Induction of pro-inflammatory cytokines (IL-1 and IL-6) and lung inflammation by Coronavirus-19 (COVI-19 or SARS-CoV-2): anti-inflammatory strategies

P Conti, G Ronconi, AL Caraffa… - J Biol Regul Homeost …, 2020 - researchgate.net
pathogenic and highly pathogenic; however, infection is not necessarily followed by the
characteristic symptoms, but can be silent (6). Low pathogenic … contrary, highly pathogenic ones. …

The four horsemen of a viral Apocalypse: The pathogenesis of SARS-CoV-2 infection (COVID-19)

P Domingo, I Mur, V Pomar, H Corominas… - …, 2020 - thelancet.com
Cytokines spill over from local inflammation to the systemic circulation. COVID-19 patients
have high serum levels of inflammatory cytokines, including interleukin (IL)-2, IL-7, IL-10, …

Severe acute respiratory syndrome (SARS) coronavirus-induced lung epithelial cytokines exacerbate SARS pathogenesis by modulating intrinsic functions of …

T Yoshikawa, T Hill, K Li, CJ Peters… - Journal of virology, 2009 - Am Soc Microbiol
… of the airway innate immune system on SARS pathogenesis. Lung epithelial cells are highly
… with SARS-CoV. We next determined the profile and the polarity of inflammatory cytokines

SARS-CoV-2 pathogenesis

MM Lamers, BL Haagmans - Nature reviews microbiology, 2022 - nature.com
pathogenesis of COVID-19. In this Review, we explore recent clinical and experimental
advances in understanding SARS-CoV-2 pathogenesis, … pro-inflammatory cytokines by triggering …

Hypothesis for potential pathogenesis of SARS-CoV-2 infection–a review of immune changes in patients with viral pneumonia

L Lin, L Lu, W Cao, T Li - Emerging microbes & infections, 2020 - Taylor & Francis
… , inflammatory cytokines, and D-Dimer show the following trends: T lymphocytes and B
lymphocytes in peripheral blood are significantly lower than before; inflammatory cytokines such …