[HTML][HTML] Mechanism involved in the pathogenesis and immune response against SARS-CoV-2 infection

U Sahu, D Biswas, AK Singh, P Khare - VirusDisease, 2021 - Springer
… -inflammatory cytokine involved in CoV-induced cytokine storm. It is recently approved in
China to decrease lung difficulties in COVID-19 patients [3]. Sarilumab monoclonal antibody is …

[HTML][HTML] The pathogenesis of coronavirus-19 disease

AC Borczuk, RK Yantiss - Journal of biomedical science, 2022 - Springer
… discuss the pathogenesis underlying organ … , SARS-CoV-2 infection stimulates Th1 cells,
Th2 cells, and Th17 cells, the net effect of which is an elaboration of pro-inflammatory cytokines, …

[HTML][HTML] SARS-CoV pathogenesis is regulated by a STAT1 dependent but a type I, II and III interferon receptor independent mechanism

MB Frieman, J Chen, TE Morrison, A Whitmore… - PLoS …, 2010 - journals.plos.org
… levels of several innate immune factors involved in pulmonary inflammation. Specifically,
we compared the induction of several pro-inflammatory cytokines (TNFα, IL6, IFNγ and MCP1) …

[HTML][HTML] Neuroinflammation and Its Impact on the Pathogenesis of COVID-19

MM Almutairi, F Sivandzade, TH Albekairi… - Frontiers in …, 2021 - frontiersin.org
cytokine levels, chemokines, and free radicals in the SARS-CoV-2-induced pathogenic
inflammatory cytokines production, including IL-6 and TNF-α (130). MiR-326 is another pro-…

[HTML][HTML] Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection

AS Tripathy, S Vishwakarma, D Trimbake, YK Gurav… - Archives of …, 2021 - Springer
… of inflammatory cytokines, known as a “cytokine storm”, correlate with disease severity and
poor prognosis during both SARS… -10 could be associated with pathogenesis of SARS-CoV-2 …

Critical determinants of cytokine storm and type I interferon response in COVID-19 pathogenesis

S Ramasamy, S Subbian - Clinical microbiology reviews, 2021 - Am Soc Microbiol
… the inflammatorycytokine storm” induction and IFN antagonism during COVID-19 pathogenesis.
… This acute surge in several inflammatory cytokines following SARS-CoV-2 infection (…

SARS‐CoV‐2: A comprehensive review from pathogenicity of the virus to clinical consequences

M Lotfi, N Rezaei - Journal of medical virology, 2020 - Wiley Online Library
… In this review article, we have collected the latest data about characteristics, pathogenesis, …
through TLR7/TLR9 to stimulate the construction of inflammatory cytokines and type I IFNs. …

SARS-CoV-2 infection and obesity: Common inflammatory and metabolic aspects

K Michalakis, I Ilias - Diabetes & Metabolic Syndrome: Clinical Research & …, 2020 - Elsevier
… -κB to the nucleus leads to a cascade of pro-inflammatory cytokines [12]. Among all interleukins,
IL-6 was found to be associated with a highly pathogenic SARS-CoV-2 infection, due to …

Role of SARS-CoV-2-induced cytokines and growth factors in coagulopathy and thromboembolism

F Ahmad, M Kannan, AW Ansari - Cytokine & Growth Factor Reviews, 2022 - Elsevier
… association of dysregulated inflammatory cytokines and GFs with … SARS-COV-1 and
MERS-CoV –induced cytokine and growth … -19 pathogenesis, SARS-COV-1 also induces a …

[HTML][HTML] Understanding the host innate immune responses against SARS-CoV-2 infection and COVID-19 pathogenesis

YW Kang, S Park, KJ Lee, D Moon, YM Kim… - Immune …, 2021 - ncbi.nlm.nih.gov
… plasma levels of inflammatory cytokines, including IL-6, IL-1β… SARS-CoV-2 is important to
uncover mechanisms of host responses and improve our knowledge for disease pathogenesis