… in the Wuhan City of China in December 2019 and evolved into a global pandemic. To date,
… release of pro-inflammatory cytokines, leading to a cytokine storm which is responsible for …

… It causes a series of clinical symptoms due to cytokine storms attacking multiple systems
and organs. In critically ill patients, they can evolve into multiple organ failure, even be life-…

… pathophysiological mechanisms causing COVID-19 respiratory and systemic disease. Spillover
of lung-derived cytokines causing a cytokine storm … extent of cytokine storm is insufficient …

… Immunoregulatory therapies target the cytokine storms induced by severe acute respiratory
… In this review, cytokine storms caused by SARS‑CoV‑2 infections are evaluated and …

… immune mechanisms and pathways behind cytokines in the cytokine storm induced by the
influenza virus. We also examined the differences of cytokine storms in different ages, sexes, …

… excessive cytokine production. The hyperinflammatory response and cytokine storm cause
… The severity could be enhanced due to viral evolution leading to the emergence of mutated …

… cytokines and eventually the development of cytokine storm … In this review, we present
evidence that a cytokine response … cause the development of cytokine storm syndrome. We also …

… worldwide investigations, the decisive pathophysiologic processes that are responsible for
… and (ii) how does each evolve over time with regard to disease progression or resolution. A …

… contributes to several pathophysiological changes in … cytokines and the creation of cytokine
storm on the infection region, hypoxia triggered simultaneously several pathophysiological …

… of cytokine storm and severe disease evolution in predisposed individuals 59 . HERV-mediated
cGAS/Sting triggering of innate inflammation in nervous tissues is a major pathogenic …