Cytokines evolution: Role in various diseases

S Kakar - Current Medicine Research and Practice, 2015 - Elsevier
pathophysiology of acute ischaemic stroke. Most of the inflammatory reactions are mediated
by cytokines… The term cytokine storm syndrome refers to the observation that multiple …

Immune cartography of macrophage activation syndrome in the COVID-19 era

D McGonagle, AV Ramanan… - Nature Reviews …, 2021 - nature.com
… these cytokine storm scenarios, the severe cytokine storm associated with superagonistic
anti-CD28 antibodies showed rapid and concurrent evolution … the close pathophysiological link …

The growth factor/cytokine midkine may participate to cytokine storm and contribute to the pathogenesis of SARS-CoV-2 infected patients

S Ketenci, Ş Aynacıoğlu - Authorea Preprints, 2021 - techrxiv.org
… contributes to several pathophysiological changes in the … cytokines and creation of cytokine
storm on the infection region, hypoxia triggered simultaneously several pathophysiological

[HTML][HTML] Pathophysiology of COVID-19: critical role of hemostasis

SA Andrade, DA de Souza, AL Torres… - Frontiers in cellular …, 2022 - frontiersin.org
… Figure 2 SARS-CoV-2 induces cytokine storm formation and increased levels of angiotensin
II. Such alterations contribute to the activation of the coagulation cascade and, consequently…

[HTML][HTML] The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
… Therefore, translating this to COVID-19 pathophysiology, cytokine storm induced Ca 2+ influx
into endothelial cells may be a contributing mechanism underpinning the disruption to inter-…

[HTML][HTML] Delayed severe cytokine storm and immune cell infiltration in SARS-CoV-2-infected aged Chinese rhesus macaques

TZ Song, HY Zheng, JB Han, L Jin, X Yang… - Zoological …, 2020 - ncbi.nlm.nih.gov
… immune responses with a more severe cytokine storm, increased infiltration of CD11b + cells,
… Thus, the delayed but more severe cytokine storm and higher immune cell infiltration may …

[HTML][HTML] Interplay of host and viral factors in inflammatory pathway mediated cytokine storm during RNA virus infection

R Chaudhary, A Meher, P Krishnamoorthy… - Current Research in …, 2023 - Elsevier
… the unpredictability of viral evolution pose a major challenge … Cytokine storm (CS) was
associated with many of these RNA … detection of the pathophysiological conditions of patients as …

Potential effects of melatonin and micronutrients on mitochondrial dysfunction during a cytokine storm typical of oxidative/inflammatory diseases

VM Martín Giménez, N de Las Heras, L Ferder… - Diseases, 2021 - mdpi.com
Cytokine storm is a severe and damaging immune reaction … production of pro-inflammatory
cytokines. This term has … The pathophysiological mechanisms underlying the cytokine

Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population

A Ciabattini, P Garagnani, F Santoro… - Seminars in …, 2020 - Springer
… of immune response to the virus, which results in a cytokine storm, with activation of the IL-6
signaling pathway. The pathophysiology of SARS-CoV-2 infection has strong similarities to …

Studying the clinical, radiological, histological, microbiological, and immunological evolution during the different COVID-19 disease stages using minimal invasive …

V D'Onofrio, L Keulen, A Vandendriessche, J Dubois… - Scientific Reports, 2022 - nature.com
… The WHO defines different COVID-19 disease stages in which the pathophysiological
These are pro-inflammatory cytokines, typically seen during cytokine storm and related to …