G Schett, B Manger, D Simon, R Caporali - Nature Reviews …, 2020 - nature.com
… inhibition in the treatment of COVID-19. Despite these similarities, COVID-19 and other zoonotic coronavirus-… COVID-19 pandemic on the treatment of patients with rheumatic diseases. …
M Abusukhun, MS Winkler, S Pöhlmann… - Frontiers in …, 2021 - frontiersin.org
… Effective treatment strategies for severe coronavirus disease (COVID-19) remain scarce. … -ceramide pathway in 23 intensive care patients with severe COVID-19. We observed an …
D Tripathi, M Sodani, PK Gupta, S Kulkarni - Current Research in …, 2021 - Elsevier
… directed therapies (HDTs) effective against viral infections with a special focus on COVID-19… -2 replication, which was confirmed with low viral load in the presence of pathwayinhibitors. …
… By inhibiting the Janus kinase (JAK)-signal transducer and activator of transcription (JAK-STAT) pathway, JAK inhibitors are hypothesized to play a role in the management of CRS in …
N Khan, X Chen, JD Geiger - Journal of cellular signaling, 2021 - ncbi.nlm.nih.gov
… and mTOR signaling pathways might provide therapeutic relief against COVID-19. Here, we … inhibit SARS-CoV-2 infectivity and thereby might be repurposed for use against COVID-19. …
XIA Lu, SHI Yujing, SU Jie, T Friedemann… - Phytomedicine, 2021 - Elsevier
… of action of SFJDC as a potential drug for the treatment of COVID-19. Furthermore, the study should determine the clinical effectiveness of SFJDC for the treatment of COVID-19. …
M Bifulco, P Gazzerro - European Heart Journal-Cardiovascular …, 2020 - academic.oup.com
… with fatal prognosis in COVID-19 infection, and growing … 183 patients with confirmed COVID-19 pneumonia in Wuhan… reduced thrombus plasminogen activator inhibitor-1 (PAI-1), …
M Hoffmann, A Sidarovich, P Arora, N Krüger… - MBio, 2022 - Am Soc Microbiol
… -CoV-2 entry into cells and its inhibition by antibodies (4), to analyze the role of amino acid residue 484 in host cell entry and its inhibition (see material and methods in the supplement). …
T Cihlar, RL Mackman - Antiviral Therapy, 2022 - journals.sagepub.com
… Baricitinib, a JAK1/2 pathwayinhibitor, was tested in a double-blind, randomized, … COVID-19 demonstrated that a short 3-day treatment with IV RDV significantly reduced COVID-19 …