The Dapagliflozin and Prevention of Adverse‐outcomes in Heart Failure (DAPAHF) trial: baseline characteristics

…, DAPAHF Committees and Investigators - … of heart failure, 2019 - Wiley Online Library
… We compared the baseline characteristics of patients in DAPA-HF with a number of recent
randomized controlled trials.18-21 Two of these had broad inclusion criteria and are shown in …

Dapagliflozin and diuretic use in patients with heart failure and reduced ejection fraction in DAPA-HF

AM Jackson, P Dewan, IS Anand, J Bělohlávek… - Circulation, 2020 - Am Heart Assoc
… In the DAPA-HF trial (Dapagliflozin and Prevention of Adverse-Outcomes in Heart Failure), …
risk of worsening heart failure and death in patients with heart failure and reduced ejection …

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
Patients who have HFrEF with or without type 2 diabetes and an … in DAPA-HF. We
calculated the incidence of the primary outcome (cardiovascular death or worsening heart failure) …

SGLT2 inhibitors in patients with heart failure with reduced ejection fraction: a meta-analysis of the EMPEROR-Reduced and DAPA-HF trials

F Zannad, JP Ferreira, SJ Pocock, SD Anker, J Butler… - The Lancet, 2020 - thelancet.com
… Using study-level published data from DAPA-HF and patient-… heart failure events and renal
outcomes in all randomly assigned patients with HFrEF and in relevant subgroups from DAPA

Effect of dapagliflozin in patients with HFrEF treated with sacubitril/valsartan: the DAPA-HF trial

SD Solomon, PS Jhund, BL Claggett, P Dewan… - Heart failure, 2020 - jacc.org
Objectives This study assessed the efficacy and safety of dapagliflozin in patients who were
or were not taking sacubitril/valsartan at baseline in the DAPA-HF (Study to Evaluate the …

Effects of dapagliflozin on symptoms, function, and quality of life in patients with heart failure and reduced ejection fraction: results from the DAPA-HF trial

MN Kosiborod, PS Jhund, KF Docherty, M Diez… - Circulation, 2020 - Am Heart Assoc
… of health status using KCCQ in the DAPA-HF trial, we observed that treatment with … the
primary composite end point of cardiovascular death or worsening HF, and its components, to a …

Effects of dapagliflozin in DAPA-HF according to background heart failure therapy

KF Docherty, PS Jhund, SE Inzucchi… - European heart …, 2020 - academic.oup.com
… the DAPA-HF trial, the SGLT2 inhibitor dapagliflozin reduced the risk of worsening heart
failure (HF) and death in patients with HF … was consistent in relation to background HF therapy. …

Dapagliflozin and recurrent heart failure hospitalizations in heart failure with reduced ejection fraction: an analysis of DAPA-HF

PS Jhund, P Ponikowski, KF Docherty, SB Gasparyan… - Circulation, 2021 - Am Heart Assoc
failure (HF) in patients with heart failure and reduced ejection fraction (HFrEF). In this analysis
of DAPA-HF, … secondary end point of total failure hospitalizations (first and recurrent) and …

Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

PS Jhund, T Kondo, JH Butt, KF Docherty… - Nature medicine, 2022 - nature.com
… planning a pooled analysis of DAPA-HF and DELIVER was to … on death from CV causes in
DAPA-HF (HR 0.82 (95% CI 0.69–… of DAPA-HF and DELIVER, the number of patients with HF

Dapagliflozin and new-onset type 2 diabetes in patients with chronic kidney disease or heart failure: pooled analysis of the DAPA-CKD and DAPA-HF trials

P Rossing, SE Inzucchi, P Vart, N Jongs… - The Lancet Diabetes & …, 2022 - thelancet.com
… Our patient-level pooled analysis of DAPA-CKD and DAPA-HF … in patients with chronic
kidney disease and heart failure, in … disease and heart failure. This is particularly relevant in …