Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study

SR Mehta, S Yusuf, RJG Peters, ME Bertrand… - The Lancet, 2001 - thelancet.com
… after percutaneous coronary intervention (PCI). We aimed to find out whether, in addition to
aspirin, pretreatment with clopidogrel followed by long-term therapy after PCI is superior to a …

Comparative benefits of clopidogrel and aspirin in high-risk patient populations: lessons from the CAPRIE and CURE studies

J Hirsh, DL Bhatt - Archives of internal medicine, 2004 - jamanetwork.com
… underwent a PCI. The aim of PCI-CURE was to determine whether clopidogrel pretreatment
… coronary syndrome undergoing PCI. At study entry, patients were randomized to receive …

Aspirin and clopidogrel in acute coronary syndromes: therapeutic insights from the CURE study

H Jneid, DL Bhatt, R Corti, JJ Badimon… - Archives of internal …, 2003 - jamanetwork.com
… was seen across all subgroups and as early as 2 days after PCI. This benefit was secondary
… was evident prior to the PCI procedure, compared with the effects of aspirin alone. No data …

Effects of aspirin dose on ischaemic events and bleeding after percutaneous coronary intervention: insights from the PCI-CURE study

SS Jolly, J Pogue, K Haladyn, RJG Peters… - European heart …, 2009 - academic.oup.com
CURE study was a randomized, double-blind trial that compared clopidogrel with placebo on
a background of aspirin in … PCI-CURE was a substudy of the CURE trial and included more …

… of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable angina …

RJG Peters, SR Mehta, KAA Fox, F Zhao, BS Lewis… - Circulation, 2003 - Am Heart Assoc
… In support of the multivariate analysis, a trend of a higher risk of bleeding with increasing
doses of aspirin is observed consistently in patients undergoing PCI, CABG, or no …

Long-term clopidogrel therapy after percutaneous coronary intervention in PCI-CURE and CREDO: the “Emperor's New Clothes” revisited

P Eriksson - European heart journal, 2004 - academic.oup.com
… 2 also suggested that pretreatment with clopidogrel in addition to aspirin is important. The …
weeks, compared with aspirin alone, in the subgroup of patients receiving clopidogrel (300 mg …

… risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non–ST-elevation acute coronary syndrome: the Clopidogrel in …

KAA Fox, SR Mehta, R Peters, F Zhao, N Lakkis… - Circulation, 2004 - Am Heart Assoc
… findings in CURE and PCI-CURE and indicate a benefit for clopidogrel treatment in those
undergoing PCI (52% with unstable angina as the presentation): by 1 year, 8.5% of clopidogrel-…

Benefit of clopidogrel according to timing of percutaneous coronary intervention in patients with acute coronary syndromes: further results from the Clopidogrel in …

…, A Budaj, S Yusuf, CURE Trial Investigators - American heart …, 2005 - Elsevier
clopidogrel therapy, timing of PCI, and cardiovascular (CV) events in patients participating in
the CURE … was lower in CURE patients who received a lower dose of aspirin, without loss of …

Antiplatelet therapy with clopidogrel and aspirin in vascular diseases: clinical evidence for and against the combination

RR Fares, LS Lansing, CA Gallati… - Expert Opinion on …, 2008 - Taylor & Francis
PCI-CURE investigators concluded that, compared to placebo, patients with non-ST
elevation MI treated with clopidogrel plus aspirin and PCI had a reduced risk of cardiovascular …

Cost-effectiveness of clopidogrel treatment in percutaneous coronary intervention: a European model based on a meta-analysis of the PCI-CURE, CREDO and PCI …

J Berg, D Fidan, P Lindgren - Current medical research and …, 2008 - Taylor & Francis
… in Unstable angina to prevent Recurrent Events (CUREaspirin and clopidogrel 75 mg daily
or aspirin and placebo for a median of 10 days before PCI, plus a loading dose of clopidogrel