Persistent activity in the prefrontal cortex during working memory

CE Curtis, M D'Esposito - Trends in cognitive sciences, 2003 - cell.com
prefrontal cortex (DLPFC) plays a crucial role in working memory. Notably, persistent activity
… The code carried by the persistent activity remains unclear, however. We critically evaluate …

Role of prefrontal persistent activity in working memory

MR Riley, C Constantinidis - Frontiers in systems neuroscience, 2016 - frontiersin.org
… of prefrontal persistent activity, with a focus on visual neurophysiology. We show that persistent
activity … We illustrate that prefrontal cortex represents features of stimuli other than their …

Persistent neuronal activity in human prefrontal cortex links perception and action

M Haller, J Case, NE Crone, EF Chang… - Nature human …, 2018 - nature.com
… cross-regional network interactions of persistent activity across a range of cognitive tasks. …
that the prefrontal cortex serves as the core element of a distributed cortical network that links …

Synaptic Basis of Persistent Activity in Prefrontal Cortex In Vivo and in Organotypic Cultures

JK Seamans, L Nogueira, A Lavin - Cerebral Cortex, 2003 - academic.oup.com
Persistent activity is observed in many cortical and subcortical brain regions, … prefrontal
cortex (PFC), neurons transiently maintain information in working memory via persistent activity

Hyperpolarization-activated graded persistent activity in the prefrontal cortex

M Winograd, A Destexhe… - Proceedings of the …, 2008 - National Acad Sciences
… In this study, we demonstrate that a different kind of graded persistent activity rooted in cellular
mechanisms occurs in neurons of the prefrontal cortex in the absence of neuromodulators…

Ethanol inhibits persistent activity in prefrontal cortical neurons

Y Tu, S Kroener, K Abernathy, C Lapish… - Journal of …, 2007 - Soc Neuroscience
… In the present study, the effects of ethanol on neuronal activity within the PFC was … of cortex
rarely show persistent activity, we used a slice coculture preparation that reproduces activity

Interplay between persistent activity and activity-silent dynamics in the prefrontal cortex underlies serial biases in working memory

J Barbosa, H Stein, RL Martinez, A Galan-Gadea… - Nature …, 2020 - nature.com
… : prefrontal multiple-unit recordings in monkeys and scalp electroencephalography (EEG)
in humans. Between successive persistent activity mnemonic codes, we found an activity-silent …

Beyond working memory: the role of persistent activity in decision making

CE Curtis, D Lee - Trends in cognitive sciences, 2010 - cell.com
… Since its first discovery in the prefrontal cortex, persistent activity during the interval between
… been identified in many cortical and subcortical areas. Such persistent activity is thought to …

Subthreshold basis for reward-predictive persistent activity in mouse prefrontal cortex

E Kim, BA Bari, JY Cohen - Cell reports, 2021 - cell.com
… Nervous systems maintain information internally using persistent activity changes. The
mechanisms by which this activity arises are incompletely understood. We study prefrontal cortex (…

Can attractor network models account for the statistics of firing during persistent activity in prefrontal cortex?

F Barbieri, N Brunel - Frontiers in neuroscience, 2008 - frontiersin.org
… Experimental evidence of persistent activity. (A) Persistent activity of a cell in IT cortex of a
monkey performing a DMS task. Raster and trial-averaged firing rate of in trials during which …