… to inhibit NLRP3 inflammasome. In the recent years, several inhibitors of NLRP3 inflammasome
… Here, we describe some recent pharmacological inhibitors of NLRP3 inflammasome …

… of action of the NLRP3 inflammasome is discussed with focus on pharmacological
inhibition of NLRP3 by small molecule inhibitors. New structural and mechanistic insights into …

… we discovered a new NLRP3 inflammasome inhibitor, a small … the formation of the NLRP3
inflammasome in vitro and limits … of this novel NLRP3 inflammasome inhibitor on cardiac …

… To date, various pharmacological inhibitors of NLRP3 inflammasome have been identified
and … of NLRP3 inflammasome activation and the reported inhibitors of NLRP3 inflammasome, …

… Thus, compounds that prevent NLRP3 inflammasome … is recent developments in NLRP3
inflammasome inhibitors. … were shown to directly inhibit NLRP3 signaling by targeting the …

… , the first pharmacologic inhibitor of the NLRP3 inflammasome to be tested in vivo. A previous
study from our group had shown that silencing of NLRP3 expression using systemic high …

… inhibiting NLRP3 inflammasome activation, thus avoiding the occurrence of serious diseases.
NLRP3 inflammasome … and inhibiting the activation of NLRP3 inflammasome and NF-κB …

… -of-concept that pharmacological inhibition of the NLRP3 inflammasome is a viable anti-…
In conclusion, this study demonstrates that pharmacological inhibition of NLRP3 with MCC950 …

… Pharmacological inhibition of NLRP3 activation results in potent therapeutic effects in a
wide variety of rodent models of inflammatory diseases, effects that are mirrored by genetic …

… Based upon this vital role of the NLRP3 inflammasome in MS … that pharmacological inhibition
of the NLRP3 inflammasome … -molecule inhibitor of the NLRP3 inflammasome that was …