Nature× nurture: Genetic vulnerabilities interact with physical maltreatment to promote conduct problems

SR Jaffee, A Caspi, TE Moffitt, KA Dodge… - Development and …, 2005 - cambridge.org
maltreated children develop conduct problems. We tested whether the effect of physical
maltreatment on risk for conduct problems was strongest among those who were at high genetic

[HTML][HTML] Genetic vulnerability to experiencing child maltreatment

P Pezzoli, J Antfolk, AS Hatoum, P Santtila - Frontiers in genetics, 2019 - frontiersin.org
… , we investigated whether genetic and … , the genetic relatedness with the perpetrator, and
the sex of the victim. Our quantitative genetic analyses supported the presence of both genetic

An investigation of child maltreatment and epigenetic mechanisms of mental and physical health risk

D Cicchetti, S Hetzel, FA Rogosch… - Development and …, 2016 - cambridge.org
… in maltreated children and indicate differences among maltreated children related to
developmental timing of maltreatment and gender in genes involved in mental health functioning. …

[HTML][HTML] The impact of childhood maltreatment: a review of neurobiological and genetic factors

E McCrory, SA De Brito, E Viding - Frontiers in psychiatry, 2011 - frontiersin.org
… Neuroendocrine, neuroimaging, and genetic factors are … of childhood maltreatment, defined
as an experience of physical, … vulnerability to (reactive) aggression following maltreatment

Research review: the neurobiology and genetics of maltreatment and adversity

E McCrory, SA De Brito, E Viding - Journal of child psychology …, 2010 - Wiley Online Library
… This work suggests that a mechanism by which MAOA genotype engenders vulnerability
to (reactive) aggression following maltreatment may include increased and poorly regulated …

Epigenetic signatures of childhood abuse and neglect: Implications for psychiatric vulnerability

CAM Cecil, RG Smith, E Walton, J Mill… - Journal of psychiatric …, 2016 - Elsevier
physical disorders (eg GABBR1, GRIN2D, CACNA2D4, PSEN2); and (iii) based on gene
ontology analyses, maltreatment … biological processes (eg physical abuse and cardiovascular …

[HTML][HTML] Gene–environment correlations and causal effects of childhood maltreatment on physical and mental health: a genetically informed approach

V Warrier, ASF Kwong, M Luo, S Dalvie, J Croft… - The Lancet …, 2021 - thelancet.com
… wide association study of childhood maltreatment with two identified genetic loci. We did
not … of gene–environment correlations or causal effects of childhood maltreatment using …

Childhood maltreatment and early developmental vulnerabilities at age 5 years

MJ Green, S Tzoumakis, B McIntyre… - Child …, 2018 - Wiley Online Library
… in middle childhood when multiple maltreatment types (physical and emotional abuse) were
… in the parents of maltreated children, but we were unable to test for genetic (inherited) risk …

Vulnerability to depression: A moderated mediation model of the roles of child maltreatment, peer victimization, and serotonin transporter linked polymorphic region …

AM Banny, D Cicchetti, FA Rogosch… - Development and …, 2013 - cambridge.org
maltreatment, peer victimization, and a polymorphism of the serotonin transporter gene (5-…
Children (M age = 11.26, SD = 1.65), including 156 maltreated and 145 nonmaltreated …

The risk for major depression conferred by childhood maltreatment is multiplied by BDNF and SERT genetic vulnerability: a replication study

B Gutiérrez, JÁ Bellón, M Rivera, E Molina… - Journal of Psychiatry and …, 2015 - jpn.ca
… (CTQ):28,29 emotional, physical and sexual abuse. These questions were shown to have
… we dichotomized emotional, physical and sexual maltreatment measures to facilitate the …