Physical phenotype of blood cells is altered in COVID-19

M Kubánková, B Hohberger, J Hoffmanns, J Fürst… - Biophysical journal, 2021 - cell.com
… The focus of this study, however, was the interrogation of changes of blood cell physical
phenotype. The following sections describe alterations of erythrocytes and leukocytes during …

Quantifying cellular differentiation by physical phenotype using digital holographic microscopy

KJ Chalut, AE Ekpenyong, WL Clegg… - Integrative …, 2012 - academic.oup.com
physical body of blood cells occur as they differentiate from myeloid precursor cells to mature
cells… 5 an important aspect of blood cell function. In the quest to understand how and when …

Altered physical phenotypes of leukemia cells that survive chemotherapy treatment

C Ly, H Ogana, HN Kim, S Hurwitz, EJ Deeds… - Integrative …, 2023 - academic.oup.com
… relevant for disease such as tumor cell invasion [16] and blood cell differentiation [31]. … To
physically phenotype cells, we extract 13 features during the sequential transit of cells through …

Multiple loci are associated with white blood cell phenotypes

MA Nalls, DJ Couper, T Tanaka, FJA van Rooij… - PLoS …, 2011 - journals.plos.org
… To further examine the functional connectivity of these loci across white blood cell
phenotypes, the Gene Relationships Among Implicated Loci package (GRAIL, http://www.broad.mit.…

Physical, biologic, and phenotypic properties of natural regulatory cells in murine bone marrow

K Dorshkind, C Rosse - American Journal of Anatomy, 1982 - Wiley Online Library
cells. In this study we have investigated whether NRC mediate their effects via cells or cell
products; analyzed their physical … and phenotypic identity (Thy-1, Ig, Ia, Fc receptors, NK cell

Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes

SC Rogers, LB Dosier, TJ McMahon, H Zhu, D Timm… - PLoS …, 2018 - journals.plos.org
… RBC phenotype was indistinguishable from that for fresh RBCs with regard to physical RBC
… % v/v glycerol final does not significantly impact RBC phenotype (compared to fresh cells). …

The allelic landscape of human blood cell trait variation and links to common complex disease

WJ Astle, H Elding, T Jiang, D Allen, D Ruklisa… - Cell, 2016 - cell.com
… genetic variants for association with 36 red cell, white cell, and platelet properties in 173,480
… (<1%) variants with a strong impact on blood cell phenotypes. Our data highlight general …

Cross-talk between red blood cells and plasma influences blood flow and omics phenotypes in severe COVID-19

SM Recktenwald, G Simionato, MGM Lopes… - Elife, 2022 - elifesciences.org
… This report illustrates a comprehensive account detailing the marked alteration of red blood
cell (RBC) morphology that occurs with COVID- 19 infection. A particularly important result is …

Understanding red blood cell parameters in the context of the frailty phenotype: interpretations of the FIBRA (Frailty in Brazilian Seniors) study

JC Silva, ZV de Moraes, C Silva… - Archives of gerontology …, 2014 - Elsevier
physical activity. This is the first description of the association between low RetAbs count and
specific frailty phenotype … is an intrinsic event in the normal aging phenotype. In our study, …

Importance of hemodynamic forces as signals for exercise-induced changes in endothelial cell phenotype

MH Laughlin, SC Newcomer… - Journal of applied …, 2008 - journals.physiology.org
… Next, we review evidence that the beneficial effects of physical activity on atherosclerosis
and CAD are the result of exercise training-induced antiatherogenic endothelial cell phenotype