The plateletfibrinogen interaction: Evidence for proximity of the Aα chain of fibrinogen to platelet membrane glycoproteins IIb/III

GA MARGUERIE, N THOMAS‐MAISON… - European journal of …, 1984 - Wiley Online Library
… Under similar conditions, 45% of the GP IIb/III from surface‐labeled platelets was recovered
… of fibrinogen comes in close proximity to GP IIb/III when the molecule is bound to its platelet

Serum amyloid A binds to fibrin (ogen), promoting fibrin amyloid formation

MJ Page, GJA Thomson, JM Nunes, AM Engelbrecht… - Scientific reports, 2019 - nature.com
… result in an increased platelet/fibrinogen interaction. The … 40 , and provides evidence of both
hypercoagulation and a pro-… antibody fluorescence is detected in close proximity to the red (…

Impact of preoperative fibrinogen concentration on postoperative outcome in patients who received dual antiplatelet therapy in proximity to off-pump coronary bypass …

NY Kim, JK Shim, JW Song, EK Kim, YL Kwak - Circulation Journal, 2014 - jstage.jst.go.jp
… complications, increasing evidence favors a certain level of platelet inhibition at the time
of … , especially in patients who received DAT in proximity to OPCAB. As our results indicate, …

Selective recognition of adhesive sites in surface-bound fibrinogen by glycoprotein IIb-IIIa on nonactivated platelets

B Savage, ZM Ruggeri - Journal of Biological Chemistry, 1991 - ASBMB
… 2) the epitope recognized by the monoclonal anti-peptide antibody may be in close proximity
but not overlapping with the … Several lines of evidence suggest that GP Ib-IX and vWF are …

Recognition of distinct adhesive sites on fibrinogen by related integrins on platelets and endothelial cells

DA Cheresh, SA Berliner, V Vicente, ZM Ruggeri - Cell, 1989 - cell.com
fibrinogen that interact with platelets and endothelial cells. We present several lines of
evidence … acids 61-203 of this subunit as being in proximity to the ligand binding domains of a& …

[HTML][HTML] Platelet collagen receptor Glycoprotein VI‐dimer recognizes fibrinogen and fibrin through their D‐domains, contributing to platelet adhesion and activation …

I Induruwa, M Moroi, A Bonna, JD Malcor… - Journal of Thrombosis …, 2018 - Elsevier
proximity between the D‐domain and collagen binding sites on GPVI‐dimer. Under low shear,
adhesion of normal platelets to D‐fragment, D‐dimer, fibrinogen … study provides evidence

[HTML][HTML] Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor

B Savage, E Saldívar, ZM Ruggeri - Cell, 1996 - cell.com
… We now demonstrate that the mechanisms initiating platelet deposition onto immobilized
fibrinogen and vWF under flow are fundamentally distinct. Fibrinogen supports attachment that …

The role of fibrinogen spacing and patch size on platelet adhesion under flow

AB Van de Walle, J Fontenot, TG Spain, DB Brunski… - Acta biomaterialia, 2012 - Elsevier
… areas and a more distant or non-existent adhesive interaction (white regions) to areas lacking
fibrinogen provides some evidence that the lateral platelet aggregate growth occurred due …

[HTML][HTML] Integrating platelet and coagulation activation in fibrin clot formation

F Swieringa, HMH Spronk, JWM Heemskerk… - Research and practice …, 2018 - Elsevier
evidence shows that α IIb β 3 can mechanically sense soluble fibrinogen versus platelet‐bound
fibrinogen … this protease to the thrombus proximity. Early findings suggested that fibrin‐…

Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.

JS Bennett, JA Hoxie, SF Leitman… - Proceedings of the …, 1983 - National Acad Sciences
… Thus, our studies provide further evidence that receptorbound fibrinogen mediates platelet
… byA2A9 is in close proximity to the platelet fibrinogen binding site. A2A9 Binding to Human …