… ancestry group (ie, when there are negligible differences in linkage disequilibrium or in
causal alleles frequencies), the prediction accuracy of polygenic scores … polygenic scores and …

… polygenic scores in different ancestry groups (above), we next assessed the performance of
polygenic scores in multiple ancestry groups… exclusively) European ancestry individuals 42 , …

… To evaluate if the increased risk is observable with increasing score or only present in the
tails of the distribution, we stratified the PRS, again standardized within each ancestry group, …

… within the traditionally defined genetic ancestry group. For example, in ATLAS we find that
501 of 504 (84 traits across 6 GIA clusters) trait–ancestry pairs have a significant associations …

… The European ancestry group was further … -ancestry was quantified and a reference group
in which we predicted the accuracy of PGS. A thorough description of how these groups were …

… To investigate the effect of sample size and ancestry composition on polygenic score …
for African-ancestry groups, given that predictive accuracy using European-ancestry PGS is …

… ancestry group: European, East Asian, and African ancestry groups utilize PCs 1 and 2, the
Admixed American group use PCs 2 and 3, and the South Asian group use PCs 4 and 5. In …

… The PRS cannot be regarded as simply a measure of the polygenic contribution to risk of
schizophrenia and clearly contains a strong ancestry component. It is possible that this could …

… for ancestry in the polygenic model using principal components (PCs), while incorporating
associations between ancestry … of ancestry in this fashion can improve polygenic prediction …

… was less strongly associated with African ancestry individuals (HRs 1.53 vs. … ancestry-specific
PRS CHD . There is a particular need for such scores in South Asians, an ancestry group …