… Both methods identify a group of patients with myeloma who have a poor prognosis, but the
S-phase determination by flow cytometry may be time-consuming and inaccurate in patients …

… common acute lymphoblastic leukemia antigen, which in separate studies has characterized
groups of patients with myeloma who had a poor prognosis 62 and those who had a good …

… IgA myeloma is associated with a poorer prognosis than IgG isotype, thought to be due to …
load being a poor prognostic factor, analysis of patients from the same Myeloma XI trial …

… , patients with a BMI of <20 kg/m 2 were of significantly poorer performance … poor tolerance
of treatment and may partly explain the poor survival outcomes. Also, only 16 % of patients in …

… with a poor prognosis in MM patients receiving intensive … impact of t(11;14) and t(4;14) in
MM in a large cohort of patients … ) was associated with poor prognosis in this group of patients. …

… cases tend to progress with more proliferative disease and poorer outcomes than cyclin…
myeloma prognosis more generally, we performed global methylation analysis on primary patient …

… poor prognostic factor; thus, we have observed that patients over 80 years of age have a much
worse prognosis than patients … of age, independently of other prognostic factors. Similarly, …

… prognostic consequence of dysregulated Class I HDAC and HDAC6, key players in multiple
myeloma (… dysregulated in MM and patients with high expression have significantly poorer …

… We extended this study in a large number of patients … patients with high LI and poor prognosis
(unpublished data). These preliminary studies show that the two most important prognostic …

… patients (10). The presence of sIL-6R greatly potentiates the proliferative effect of IL-6 …
myeloma cells. Therefore, the finding that patients with high levels of sIL6R have a poor prognosis …