Porphyromonas gingivalis in Alzheimer's disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

…, S Kaba, A Lee, MI Ryder, B Potempa, P Mydel… - Science …, 2019 - science.org
Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in
the brain of Alzheimer’s disease patients. Toxic proteases from the bacterium called …

Assessing the role of Porphyromonas gingivalis in periodontitis to determine a causative relationship with Alzheimer's disease

SK Singhrao, I Olsen - Journal of oral microbiology, 2019 - Taylor & Francis
… vivo infection-mediated periodontal disease models supporting the antimicrobial protection
… studies supporting the causal links. Oral infections with Porphyromonas gingivalis, or …

Porphyromonas gingivalis

L Reyes - Trends in Microbiology, 2021 - cell.com
… In addition to being a causative agent of periodontitis, P. gingivalis is also implicated in a
variety of systemic diseases such as cardiovascular disease, Alzheimer’s disease, and …

Microbial interaction of periodontopathic bacterium Porphyromonas gingivalis and HIV-possible causal link of periodontal diseases to AIDS progression

K Imai, A Florence B Victoriano, K Ochiai… - Current HIV …, 2012 - ingentaconnect.com
… Periodontal disease, caused by subgingival infection with oral anaerobic bacteria, typically
Porphyromonas gingivalis (P. gingivalis) belonging to the phylum Bacteroidetes, is found …

Porphyromonas gingivalis, Periodontal and Systemic Implications: A Systematic Review

L Fiorillo, G Cervino, L Laino, C D'Amico, R Mauceri… - Dentistry journal, 2019 - mdpi.com
… health and systemic diseases are a topic of discussion. Porphyromonas gingivalis is one of
the … important role in the progression of periodontal disease. In this systematic review authors …

Porphyromonas gingivalis and Its Systemic Impact: Current Status

F Mei, M Xie, X Huang, Y Long, X Lu, X Wang, L Chen - Pathogens, 2020 - mdpi.com
… is involved in the onset or exacerbation of diseases, together with its effects on systemic
health… Porphyromonas gingivalis should be regarded as a modifiable factor for several diseases. …

Porphyromonas gingivalis Virulence Factors and Clinical Significance in Periodontal Disease and Coronary Artery Diseases

LH Aleksijević, M Aleksijević, I Škrlec, M Šram, M Šram… - Pathogens, 2022 - mdpi.com
Porphyromonas gingivalis is a gram-negative, anaerobic bacterium that lives in the oral …
factor in the development of periodontal disease. During various therapeutic procedures, P. …

Porphyromonas gingivalis and Alzheimer disease: Recent findings and potential therapies

MI Ryder - Journal of periodontology, 2020 - Wiley Online Library
… the teeth and is associated with various systemic disorders.However, establishing a definitive
causal link between periodontitis and extraoral disease such as AD, versus a simple associ…

Porphyromonas gingivalis Periodontal Infection and Its Putative Links with Alzheimer's Disease

SK Singhrao, A Harding, S Poole… - Mediators of …, 2015 - Wiley Online Library
… Periodontal disease (PD) and Alzheimer’s disease (AD) are … Chronic PD involves major
pathogens (Porphyromonas gingivalis, Treponema … The causal bacteria typically include P. …

[PDF][PDF] Causation and pathogenesis of periodontal disease

DF Kinane - Periodontology 2000, 2001 - academia.edu
… the causation and pathogenesis of periodontal disease in a … in the causation and pathogenesis
of periodontal disease will be re… tissues and disease susceptibility. The term ‘‘periodontal …