Y Cao, B Su, X Guo, W Sun, Y Deng, L Bao, Q Zhu… - Cell, 2020 - cell.com
… Moreover, we demonstrated that SARS-CoV-2-neutralizingantibodies could be directly … CoV-neutralizingantibodies. Altogether, we showed that human neutralizingantibodies could be …
… to be a requirement for potentneutralization. The most potent NAbs both targeted the RBD on … Although direct comparisons are difficult, the neutralizationpotency of these and several …
LM Walker, SK Phogat, PY Chan-Hui, D Wagner… - Science, 2009 - science.org
… Here, we have confirmed that this region serves as a potentneutralization target and demonstrated that antibodies that recognize conserved parts of V2 and V3 can have broad reactivity…
AI Flyak, X Shen, CD Murin, HL Turner, JA David… - Cell, 2016 - cell.com
… We isolated a large panel of human monoclonal antibodies (mAbs) against BDBV glycoprotein (… We determined that a large proportion of mAbs with potentneutralizing activity against …
… main target of neutralizingantibodies. Here we describe multiple monoclonal antibodies targeting SARS-… One antibody, named S309, potently neutralizes SARS-CoV-2 and SARS-CoV …
… neutralizationpotency and breadth can be achieved without extraordinary levels of somatic hypermutation. Although some neutralizingantibodies … HIV-1 neutralization breadth within …
… of the mAbs neutralize live EBOV, and several mAbs exhibit unprecedented potency. Structures … Neutralizingantibodies targeting this site show potent therapeutic efficacy against lethal …
R Kong, H Li, F Bibollet-Ruche, JM Decker… - Journal of …, 2012 - Am Soc Microbiol
… antibodyneutralization. We characterized the potency and breadth of neutralizingantibody (… 7312A proviral backbone showed potentneutralization of all but 4 viruses. The specificity of …
… Although neutralizingantibodies have been found that bind a single, so-called supersite … and usually less potent than the best ACE2 blockers, neutralizingantibodies have also been …