[HTML][HTML] Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target

H Zhang, JM Penninger, Y Li, N Zhong… - Intensive care medicine, 2020 - Springer
… They further demonstrated that SARS-CoV-2 does not use other coronavirus receptors
SARS-CoV-2 spike protein directly binds with the host cell surface ACE2 receptor facilitating virus

[HTML][HTML] Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

Y Huang, C Yang, X Xu, W Xu, S Liu - Acta Pharmacologica Sinica, 2020 - nature.com
… The spike (S) protein of SARS-CoV-2, which plays a key role in the receptor recognition and
… a coronavirus later named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) […

[PDF][PDF] Potential natural compounds for preventing SARS-CoV-2 (2019-nCoV) infection

H Chen, Q Du - 2020 - researchgate.net
2019-nCoV share some common sequence with SARS-CoV, and used the same host receptor
ACE2, we review the potential active compounds for anti-SARSCoV, and at the same time…

Receptor recognition by the novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS coronavirus

Y Wan, J Shang, R Graham, RS Baric, F Li - Journal of virology, 2020 - Am Soc Microbiol
SARS-CoV. Here, we analyzed the potential receptor usage by 2019-nCoV, based on the rich
… about SARS-CoV and the newly released sequence of 2019-nCoV. First, the sequence of …

Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARSCoV2

Z Liu, X Xiao, X Wei, J Li, J Yang, H Tan… - Journal of medical …, 2020 - Wiley Online Library
SARS-CoV-2 with SARS-CoV, bat SARS-like CoV, and other coronaviruses, which are helpful
for evolutionary analysis and finding the possible virus … to differentiate the potential hosts. …

Prospect of SARS-CoV-2 spike protein: Potential role in vaccine and therapeutic development

SK Samrat, AM Tharappel, Z Li, H Li - Virus research, 2020 - Elsevier
… the receptor-binding domain of SARS-CoV-2 binds more strongly to the ACE2 receptor than
that of SARS-CoV, making it a more suitable target for the development of virus attachment …

[HTML][HTML] A potential role for integrins in host cell entry by SARS-CoV-2

CJA Sigrist, A Bridge, P Le Mercier - Antiviral research, 2020 - ncbi.nlm.nih.gov
… We suggest that SARS-CoV-2 may also use integrins as cell receptors in one or more host
… in the receptor-binding domain of the spike proteins of all SARS-CoV-2 sequences analyzed …

[HTML][HTML] Understanding SARS-CoV-2-mediated inflammatory responses: from mechanisms to potential therapeutic tools

Y Fu, Y Cheng, Y Wu - Virologica Sinica, 2020 - Springer
… C Potential therapeutics based on targeting the Fc receptors to block SARS-CoV-2-induced
inflammatory responses. From left to right, FcR can be blocked using anti-Fc specific …

[HTML][HTML] Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

C Wu, Y Liu, Y Yang, P Zhang, W Zhong… - … Pharmaceutica Sinica B, 2020 - Elsevier
… In addition, viruses often bind to receptor proteins on the … , the SARS virus binds to the
angiotensin-converting enzyme 2 (… the host receptor of SARS-CoV-2 is consistent with SARS-CoV, …

Therapeutic potential of miRNAs targeting SARS-CoV-2 host cell receptor ACE2

I Bozgeyik - Meta gene, 2021 - Elsevier
… to reveal potential miRNA targets for the regulation of SARS-CoV-2 host cell receptor ACE2.
… , it was aimed to reveal potential miRNA targets for the regulation of SARS-CoV-2 host cell …