Cholinergic nicotinic systems in Alzheimer's disease: prospects for pharmacological intervention

R Vesey, JM Birrell, C Bolton, RS Chipperfield… - CNS drugs, 2002 - Springer
potential involvement of the nicotinic cholinergic system in Alzheimer’s disease and discusses
the possibility of nicotinic … [113] M 2 antagonists therefore have potential therapeutic value …

Targeting the cholinergic system as a therapeutic strategy for the treatment of pain

PG Jones, J Dunlop - Neuropharmacology, 2007 - Elsevier
… between the nicotinic and adrenergic systems in the female since the nicotinic component …
the discovery of novel NNR agonists for potential therapeutic utility in pain. Resulting from an …

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

EJ Mufson, SE Counts, SE Perez… - Expert review of …, 2008 - Taylor & Francis
… A NGF gene therapy trial reduced cognitive decline and stimulated cholinergic fiber growth
in … be considered for a more comprehensive treatment approach for cholinergic dysfunction. …

[HTML][HTML] Nicotinic cholinergic system and COVID-19: In silico evaluation of nicotinic acetylcholine receptor agonists as potential therapeutic interventions

N Alexandris, G Lagoumintzis, CT Chasapis… - Toxicology reports, 2021 - Elsevier
… be an intriguing therapeutic approach for the COVID-19s' pandemic. Cholinergic agonists
may … , we suggest that the potential therapeutic effects of nicotine or other cholinergic agonists, …

[HTML][HTML] Nicotinic cholinergic system and COVID-19: in silico identification of an interaction between SARS-CoV-2 and nicotinic receptors with potential therapeutic …

K Farsalinos, E Eliopoulos, DD Leonidas… - International journal of …, 2020 - mdpi.com
… , the nicotinic cholinergic system. We also provide insight about the potential therapeutic role
of … The possibility that other chemicals besides nicotine may be associated with a potentially

Therapeutic potential of α7 nicotinic acetylcholine receptors

D Bertrand, CHL Lee, D Flood, F Marger… - Pharmacological …, 2015 - ASPET
… has identified the forebrain cholinergic system as being important in many higher order
brain functions. Further analysis of the genes encoding the nicotinic acetylcholine receptors (…

Nicotine and the nicotinic cholinergic system in COVID‐19

Y Tizabi, B Getachew, RL Copeland… - The FEBS …, 2020 - Wiley Online Library
… , on the other hand, we support a potential therapeutic role for nicotine, nicotinic agonists,
or positive allosteric modulators of nicotinic cholinergic receptors in COVID-19, owing to their …

Acetylcholine and the alpha 7 nicotinic receptor: a potential therapeutic target for the treatment of periodontal disease?

N Zoheir, DF Lappin, CJ Nile - Inflammation Research, 2012 - Springer
… for a functional cholinergic system in the periodontium. In addition, we will describe the potential
… and examine the potential of cholinergic based therapies in order to treat the condition. …

[HTML][HTML] Nicotinic receptor intervention in Parkinson's disease: future directions

Y Tizabi, B Getachew - Clinical pharmacology and translational …, 2017 - ncbi.nlm.nih.gov
… In summary, nicotine has a great potential in PD treatment due to its neuroprotective and
other positive properties. It may not only address the movement symptoms, but also the mood …

Targeting the nicotinic cholinergic system to treat attention-deficit/hyperactivity disorder: rationale and progress to date

AS Potter, G Schaubhut, M Shipman - CNS drugs, 2014 - Springer
… of nicotine on cognition has spurred research into the therapeutic potential of nicotinic agents
… Although there are no approved medications for ADHD that target nicotinic acetylcholine …