… of novel therapeutics toward efficacious management of COVID-19 cytokine storm and other
… functions while guaranteeing cytokine mobility for potent cytokine neutralization. Meanwhile…

… to cytokine storm, the acute systemic inflammatory syndrome present in a subgroup of COVID‐19
patients. Cytokine storm … Therefore, we propose a unifying definition of cytokine storm‐…

… therapies aimed at alleviating the cytokine storm originated … show a strong time dependence
between cytokine levels and … the best strategy to characterize the evolution of the cytokine …

… and may provide a standard tool for drug discovery initiatives … , we assemble and score
multidrug therapies based on their … the most robust and direct disruption of cytokine storm and to …

… been the lack of diagnostic tools to evaluate immune function … and robust inflammatory
response and worsen organ injury. … an immunoadjuvant therapy to restore COVID-19–induced T …

… histories reflect not only the natural reactions of the subjects but their response to therapy. …
At best, we can estimate probability distributions of the concentrations and their rates. …

… cytokines suggest that a cytokine storm, also known as … existing therapies for CRS. We
propose to utilize interleukin-6 (… but robust type I IFN response and releasing other inflammatory …

… a ‘cytokine storm’. This review focuses on the pathological role of IL-6 in a cytokine storm and
the therapeutic effect of IL-6 … VE-cadherin and has a potent vascular permeability effect on …

… the major cause of inflammatory cytokine storm, and thereby … cytokine storm and inflammatory
complex including IL-6, tumor … IL-6 is a potent pro-inflammatory cytokine that plays a crucial …

… syndrome (ARDS), and cytokine storm. A significant proportion of patients … therapy (LLLT)
has strong, anti-inflammatory effects confirmed by meta-analyses, and it may be therapeutic …