… antithrombotic therapy and is part of the American College of Chest Physicians Evidence-Based
Clinical Practice Guidelines … recommend bridging anticoagulation with therapeutic-dose …

Background High-quality anticoagulation management is required to keep these narrow
therapeutic index medications as effective and safe as possible. This article focuses on the …

… The antithrombotic effect of each oral anticoagulant drug, the interactions, and the … and
optimal dosages of oral anticoagulant therapies, practical issues related to their initiation and …

Background Antithrombotic therapy is efficacious for the prevention of thromboembolic disease,
but it necessitates careful risk-benefit assessment. Methods Antithrombotic therapy data …

… used in clinical practice. It is also the dose regimen that we consider most important for
practice guidelines because it has the potential to confer the greatest therapeutic benefit and the …

… transient risk factor, we recommend 3 months of therapy (Grade 1B; Grade 2B if provoked …
therapy if bleeding risk is low or moderate (Grade 2B) and recommend 3 months of therapy if …

… for antithrombotic therapy. These ratings guided value and preference decisions underlying
the recommendations. Each topic panel identified questions in which resource allocation …

… no therapy rather than antithrombotic therapy, and for patients choosing antithrombotic
therapy, we suggest aspirin rather than oral anticoagulation or combination therapy with aspirin …

… , we recommend long-term antithrombotic therapy (Grade 1A), … , we recommend long-term
aspirin therapy at a dose of 75–… , we recommend that antithrombotic therapy decisions follow …

… In patients with a history of stroke or TIA and atrial fibrillation we recommend oral
anticoagulation over no antithrombotic therapy, aspirin, and combination therapy with aspirin and …