SL Groenland, RHJ Mathijssen, JH Beijnen… - European Journal of …, 2019 - Springer
… Imaging is usually performed every 8 to 12 weeks, while ideally doseadjustments should … of tumor cells have already emerged and doseadjustments will probably be too late at this …
AK Lyashchenko, S Cremers - British journal of clinical …, 2021 - Wiley Online Library
… Precisiononcology approaches have enabled matching of the best available anticancer … of TDM-guided precisiondosing, ie adjusting an individual's drug dose based on measured …
… For every iteration, the agent then selects an action, for example, a doseadjustment on a linear scale from 0 to 100%, given the state of the environment. This action will result in an …
M Nikanjam, S Kato, JK Sicklick, R Kurzrock - European Journal of Cancer, 2023 - Elsevier
… cancer drugs is based on giving each patient the same dose (a flat dose) or a dose based … drug dosing determined by starting at reduced doses and using intrapatient dose escalation …
SL Groenland, RB Verheijen, M Joerger… - Clinical Cancer …, 2021 - AACR
… The purpose of this perspective is to discuss whether randomized studies are needed to confirm the clinical value of precisiondosing in oncology. PK-based doseadjustments are …
V Vashistha, E Katsoulakis, A Guo, M Price… - … Precision Oncology, 2023 - ascopubs.org
… Time to first doseadjustment refers to reduction in dose, treatment break, or treatment … Although the classification schema varies across the available precisiononcology information …
… Dose calculation based on body size (weight or surface area) could be described as implementing a doseadjustment… examples in cancer treatment of doseadjustment based on a …
… dose reduction guidelines for severe toxicity and adjustment of monoclonal antibody dose according to body size, 1 precisiondosing … the potential for precisiondosing of targeted cancer …
V Prasad, T Fojo, M Brada - The Lancet Oncology, 2016 - thelancet.com
… of precisiononcology alongside those of precision diagnostics … , will have to undergo substantive adjustments before it can be … Treatment interruptions or dose delays—a marker of …