The Induction of Proinflammatory Cytokines in Response to Avian Influenza H5N1 Infections and their Role in Pathogenesis and the Enhancement of Virulence

MD Wareing, GA Tannock - … & Anti-Allergy Agents in Medicinal …, 2008 - ingentaconnect.com
determinants of H5N1-mediated pathology, is dysfunctional cytokine production resulting in
a cytokine storm… HA surface antigen – the primary determinant of immunological protection. …

[HTML][HTML] Involvement of Bradykinin and Folate receptor in calming the SARS-COV2 cytokine storm: Lessons learnt from lung cancer

P Gowda, E Sen - 2020 - europepmc.org
… the primary involvement of lungs in Coronaviruses (CoV) associated deaths [1]. Cytokine storm
… As the host response plays a determinant role in the pathogenesis of infectious diseases, …

[PDF][PDF] Tocilizumab as a Treatment for Cytokine Storm in COVID-19 Patients: A systematic review

MH Haron, MR Isa, HS Mohd Rashid… - J Pub Health Issue …, 2022 - researchgate.net
… 19-related hyperinflammatory state, known as a cytokine storm. This systematic review was
conducted to study the treatment of cytokine storm by Tocilizumab in COVID-19 patients. The …

[HTML][HTML] Common determinants of severe Covid-19 infection are explicable by SARS-CoV-2 secreted glycoprotein interaction with the CD33-related Siglecs, Siglec-3 …

SH Murch - Medical hypotheses, 2020 - Elsevier
… The primary tropism of the SARS-CoV-2 virus is for angiotensin converting enzyme-2 (ACE-…
of ongoing disease such as late-onset cytokine storm and frequent vascular thromboses. …

Cascade of immune mechanism and consequences of inflammatory disorders

KB Megha, X Joseph, V Akhil, PV Mohanan - Phytomedicine, 2021 - Elsevier
cytokines interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) acts
as primary … Therefore, the timely treatment for cytokine storm has become an essential part …

Polyphosphazene nanodrugs for targeting delivery and inflammation responsive release of curcumin to treat acute lung injury by effectively inhibiting cytokine storms

X Su, X Jing, W Jiang, M Li, K Liu, M Teng, Y Ma… - Colloids and Surfaces B …, 2023 - Elsevier
… by cytokine storms is the primary reason … cytokine storm syndrome and alleviates inflammation
in the infected cells and tissues by down-regulating several critical inflammatory cytokines

Higher levels of IL-1ra, IL-6, IL-8, MCP-1, MIP-3α, MIP-3β, and fractalkine are associated with 90-day mortality in 132 non-immunomodulated hospitalized patients with …

L Rabøl Andersen, B Hindsberger, S Bastrup Israelsen… - Plos one, 2024 - journals.plos.org
… The primary outcome was death within 90 days from admission … of cytokines and secondary
organ damage. This phenomenon, designated cytokine release syndrome or cytokine storm (…

[HTML][HTML] Triggers, timescales, and treatments for cytokine-mediated tissue damage

DA McBride, MD Kerr, NC Dorn… - European medical …, 2021 - ncbi.nlm.nih.gov
… by a ‘cytokine storm’ are observed in cytokineprimary determinant of disease progression
and clinical outcome is the host immune response, which involves the generation of cytokines, …

Differential susceptibilities of human lung primary cells to H1N1 influenza viruses

E Travanty, B Zhou, H Zhang, YP Di, JF Alcorn… - Journal of …, 2015 - Am Soc Microbiol
… Influenza virus HA protein is the main determinant of virus … proinflammatory cytokines IL-1β,
TNF-α, IFN-γ, and IL-6 and … that an excessive cytokine response, or cytokine storm, is …

COVID-19 and the role of cytokines in this disease

A Hasanvand - Inflammopharmacology, 2022 - Springer
… lymphocyte concentrations, which caused a cytokine storm in these patients. This inverse …
Primary and important cytokines include those that can play an important role in the types of …