Recapitulating kidney development: Progress and challenges

MH Little, SV Kumar, T Forbes - Seminars in cell & developmental biology, 2019 - Elsevier
… provides some challenges for the identification of regenerated human kidney cell types in vitro
… human renal cell types draw heavily on our understanding of murine kidney development. …

[HTML][HTML] Achievements and challenges in bioartificial kidney development

F Tasnim, R Deng, M Hu, S Liour, Y Li, M Ni… - Fibrogenesis & tissue …, 2010 - Springer
… from which the kidneys arise during embryonic development, by … for the proper development
of kidney tubules in mice [124, … role in various types of human cystic kidney diseases [126]. It …

[HTML][HTML] A critical review of current progress in 3D kidney biomanufacturing: advances, challenges, and recommendations

NM Wragg, L Burke, SL Wilson - Renal Replacement Therapy, 2019 - Springer
… have shown that more development is required for market progression. Tissue … kidney
structure, previous attempts have fallen short. With the recent development and progression of 3D …

[HTML][HTML] Stem cell therapies in kidney diseases: progress and challenges

C Rota, M Morigi, B Imberti - International journal of molecular sciences, 2019 - mdpi.com
… purposes, including understanding kidney development, the mechanisms of kidney diseases,
the in vitro derivation of kidney disease models, and last but not least, for therapeutic use. …

Human kidney organoids: progress and remaining challenges

R Nishinakamura - Nature Reviews Nephrology, 2019 - nature.com
… and signals underlying kidney development. The availability … of kidney organoids to the
process of kidney development in vivo… Kidney organoids have the potential to advance the field of …

[HTML][HTML] Diabetic kidney disease: challenges, progress, and possibilities

RZ Alicic, MT Rooney, KR Tuttle - Clinical journal of the American …, 2017 - journals.lww.com
… of diabetic kidney disease onset and progression. Therefore, … for patients with diabetic
kidney disease. Achieving this goal … , and development of therapeutic agents targeting kidney-…

[HTML][HTML] Sustainable development goals relevant to kidney health: an update on progress

VA Luyckx, Z Al-Aly, AK Bello, E Bellorin-Font… - Nature Reviews …, 2021 - nature.com
… framework to discuss current progress and remaining challenges. A more detailed discussion
of how each SGD might impact the risk of specific kidney disorders is found elsewhere 3 . …

[HTML][HTML] Diabetic kidney disease: challenges, advances, and opportunities

Y Chen, K Lee, Z Ni, JC He - Kidney diseases, 2020 - karger.com
… are well treated may have relatively stable kidney function or progression at a very slow rate.
… may contribute to progression to ESRD in patients with diabetes is acute kidney injury (AKI). …

… drug development challenges in chronic kidney disease (CKD)—identification of individualized determinants of renal progression and premature cardiovascular …

I Formentini, M Bobadilla, C Haefliger… - Nephrology Dialysis …, 2012 - academic.oup.com
… to slow down the progression of CKD and reduce CVD … progress to ESRD and/or die from
CVD whereas others rather remain stable. In this article, we urge renal researchers to develop

The growing challenge of chronic kidney disease: an overview of current knowledge

R Borg, N Carlson, J Søndergaard… - International Journal of …, 2023 - Wiley Online Library
progression of the disease and delaying kidney failure. Although many attempts have been
made to develop … with regards to delaying the progression of kidney outcome. In nondiabetic …