Tissue-based research in kidney cancer: current challenges and future directions

S Signoretti, G Bratslavsky, FM Waldman… - Clinical cancer …, 2008 - AACR
… In the past few years, considerable progress has been made in the treatment of kidney
cancer. Novel treatments targeting molecular pathways known to be dysregulated in this disease …

Kidney disease in China: recent progress and prospects

X Yu, J Wei - Chinese medical journal, 2009 - journals.lww.com
… risk factors for the development of progressive renal dysfunction. The challenge is to identify
the … The focus of this review will be on selected topics where substantial progress in our …

Kidney organoid systems for studies of immune-mediated kidney diseases: challenges and opportunities

MC Stein, F Braun, CF Krebs, MJ Bunders - Cell and tissue research, 2021 - Springer
… in the development of kidney organoid models, including pluripotent stem cell-derived kidney
… Further progress was achieved by selective induction of nephron progenitors, ureteric bud, …

The clinical usefulness of glycated albumin in patients with diabetes and chronic kidney disease: progress and challenges

T Gan, B Liao, G Xu - Journal of Diabetes and its Complications, 2018 - Elsevier
… Thus, checking and maintaining low glycated albumin levels would prevent the formation
of AGE and may be useful to prevent the occurrence or progression of diabetes or …

Enhancing Kidney vasculature in tissue engineering—Current trends and approaches: A Review

CG Lebedenko, IA Banerjee - Biomimetics, 2021 - mdpi.com
… The development of in vitro kidney organoids is possible … cellular basis of embryonic kidney
development. Furthermore, the … One area of technology that has seen great progress in the …

Approaches to kidney replacement therapies—opportunities and challenges

B Huang, Z Zeng, CC Zhang… - Frontiers in Cell and …, 2022 - frontiersin.org
… In this review, we introduce the concept and summarize the progress of the current … led to
the creation of various kidney organoids that model kidney development and disease in vitro. …

Role of renal urothelium in the development and progression of kidney disease

AR Carpenter, KM McHugh - Pediatric nephrology, 2017 - Springer
… Although expression of Upk1b, or any other Upk protein for that matter, has never been
reported during the early stages of kidney development, recent data from our lab show that …

The next generation of therapeutics for chronic kidney disease

MD Breyer, K Susztak - Nature reviews Drug discovery, 2016 - nature.com
development that target haemodynamic changes in CKD. Smoking cessation also slows the
rate of progression … address key challenges and considerations in the development of novel …

[HTML][HTML] The impact of kidney development on the life course: a consensus document for action

TLB Weight… - Nephron. Clinical …, 2017 - ncbi.nlm.nih.gov
… important determinants of healthy pregnancies and impact kidney development [15, 99]. These
… Examples of primary kidney diseases that progress more rapidly in patients with low birth …

The novel mineralocorticoid receptor antagonist finerenone in diabetic kidney disease: progress and challenges

P Yang, T Huang, G Xu - Metabolism, 2016 - Elsevier
… In conclusion, in order to address their roles in delaying the development of end-stage
renal disease, atrasentan and finerenone have led to larger phase III trials [75]. And, it was …