… -brain-barrier integrity. Thus, cellular senescence can serve as a primary therapeutic target
… This review summarizes the concept of cellular senescence, its role in the aging brain, and …

… the aging brain, the decline in the normal flow of the autophagic flux has been associated
with brain aging [… support autophagy as a promising therapeutic target in brain aging and age-…

… -targeted rechargeable antioxidants are promising as tools to treat brain pathologies … These
unique properties of mitochondria-targeted rechargeable antioxidants make them promising …

… application, although targeting miRNA is a promising treatment strategy for aging, a fully …
and diagnosis and is a promising target for cancer therapy [155]. However, aging-related let-7 …

… , compensation and effective interventions holds promise for a more optimistic view of …
aging brain. Here, we review several key chapters to this developing story: neurocognitive aging …

… promising research target in a number of brain pathologies. This review describes updated
results on sirtuins in brain aging/… Likewise, in the aged brain diminished SIRT6 binding could …

… major aging pathways that have been discovered, target of rapamycin (TOR) signaling and
Sirtuin 1-dependent protein deacetylation, may be linked not only to normal aging processes …

… the blood–brain barrier and glucose metabolism serve as markers of early AD, but this may
be a key player in dementia pathology and a promising therapeutic target for the prevention …

… oxidative stress increases in aging brain. Rigorous studies show … (NSAIDs) show significant
promise. Vitamin E supplementation … processes show great promise for abating dementia …

… of neurodegenerative diseases but also promise to make biological rejuvenation feasible.
We will first review recent evidence supporting the emerging view that aging is a reversible …