Cytokine storm and the prospects for immunotherapy with COVID-19.

LH Calabrese - Cleveland Clinic journal of medicine, 2020 - europepmc.org
… often referred to as "cytokine storm." While the immunopathogenesis remains unclear,
prospects of treating this severe phase of the illness with immunotherapy are evolving, with some …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

[HTML][HTML] The 'cytokine storm': molecular mechanisms and therapeutic prospects

R Karki, TD Kanneganti - Trends in immunology, 2021 - cell.com
Cytokine storm syndrome (CSS) has generally been described as a collection of clinical
manifestations resulting from an overactivated immune system. Cytokine storms (CSs) are …

[HTML][HTML] Immunotherapy summary for cytokine storm in COVID-19

Y Li, W Zhao, J Liu, Z Chen, Q Lv… - Frontiers in Pharmacology, 2021 - frontiersin.org
… This paper focuses on the mechanism of CS induced by the SARS-CoV-2 virus and its
clinical manifestations, and reviews the recently reported immunotherapies for cytokine storm, …

[HTML][HTML] Clinical cancer immunotherapy: Current progress and prospects

C Liu, M Yang, D Zhang, M Chen, D Zhu - Frontiers in immunology, 2022 - frontiersin.org
immunotherapy has shown remarkable efficacy, it also suffers from limitations such as irAEs,
cytokine storm, … , and limitations of cancer immunotherapy. Besides, by combining cancer …

[HTML][HTML] Immunotherapy strategies and prospects for acute lung injury: Focus on immune cells and cytokines

W Zhu, Y Zhang, Y Wang - Frontiers in Pharmacology, 2022 - frontiersin.org
… and inflammatory storms, the application of immunotherapy will have a high prospect. Just as
a … subpopulation that promotes the inflammatory cytokine storms by using single-cell mRNA …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
… immune system, cytokines may become harmful to the body, leading to a state of systemic
hyperinflammation called a cytokine storm [1]. Cytokine storm underlies several pathological …

[HTML][HTML] Immunoregulatory therapy strategies that target cytokine storms in patients with COVID‑19

X Wang, Z He, X Zhao - Experimental and Therapeutic …, 2021 - spandidos-publications.com
… Immunoregulatory therapies target the cytokine storms induced by severe acute respiratory
… In this review, cytokine storms caused by SARS‑CoV‑2 infections are evaluated and …

[HTML][HTML] Radiotherapy and cytokine storm: risk and mechanism

C Zhang, Z Liang, S Ma, X Liu - Frontiers in Oncology, 2021 - frontiersin.org
… responses induced by radiation, especially the cytokine storm and the underlying mechanisms
such as DAMPs release, pro-inflammatory cytokine secretion and cGAS-STING pathway …

PROSPECTS FOR IMMUNOTHERAPY TREATMENT AGAINST COVID-19 INFECTION

N KUKULADZE… - Experimental and Clinical …, 2022 - journals.4science.ge
… Other Janus kinase (Ruxolitinib(30), TofacitinibNoclinical trials to date) as well as Bruton's
Tyrosine kinase inhibitors were used or proposed to do so to treat cytokine storm in COVID-19 …