… heterogeneity of CAFs and their effects on tumor progression can vary widely with the
presence of … tumor progression. CAFs contribution to tumor progression: one size does not fit all …

… -microenvironment interaction has a decisive role in controlling local cancer growth, … in
prostate cancer cells alone are not enough to confer metastatic status without a supporting tumor …

… in prostate cancer pathogenesis in a biological and clinical context and demonstrates how
integrated analysis of high-throughput data augments our understanding of prostate cancer. …

… prostate cancer, we screened 667 miRNAs in serum samples from patients with metastatic (n
= 7) and localized prostate cancer … set taken from different prostate cancer risk groups. Most …

… target for prostate cancer prevention and treatment, but more recently estrogens and their
receptors have also been implicated in prostate cancer development and tumor progression. …

… For example, loss of the tumor-suppressor, p53, in concert with PTEN loss increases tumor
progression rate and drives lethal PCa progression. Additionally, overexpression of human …

… To begin to explore the molecular changes involved in tumor progression, we used the
RNase protection assay to compare the levels ofp53, Rb, c-myc, and bcl-2 gene products in …

… prostate cancer, the genetic alterations and biological processes that correlate with the
observed histological progression … , we have profiled prostate cancer progression from benign …

… genes involved in progression of prostate cancer, molecular markers may offer additional
hallmarks of cancer progression and our failure to cure this all-too-common cancer. So far, …

… consist of a dynamic tumor microenvironment during prostate cancer progression. Indeed, …
from prostate tumors can stimulate tumor progression of non-transformed prostate epithelial …