Protective activity of biflavanones from Garcinia kola against Plasmodium infection

B Konziase - Journal of ethnopharmacology, 2015 - Elsevier
Plasmodium falciparum (FCR-3, cycloguanil-resistant strain … in vitro assessments of antimalarial
activities. Growth inhibition, … activities were determined in mice infected with Plasmodium

Aldolase Activity of a Plasmodium falciparum Protein with Protective Properties

U Certa, P Ghersa, H Döbeli, H Matile, HP Kocher… - Science, 1988 - science.org
Plasmodium falciparum induces immunity to malaria in monkeys. However, antigenic
polymorphism and repetitive amino acids commonly found in protective … showed aldolase activity. …

A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum

N Beutler, T Pholcharee, D Oyen… - PLoS …, 2022 - journals.plos.org
falciparum. We obtained crystal structures of the Fab fragments for five of these antibodies …
-parasite activity by conducting an in vivo protection study in mice using transgenic P. berghei …

Towards the development of a fully protective Plasmodium falciparum antimalarial vaccine

ME Patarroyo, A Bermudez… - Expert Review of …, 2012 - Taylor & Francis
… Its partial protective efficacy and low or non-protective activity in the newborn led to us
deciding to halt further clinical trials with this vaccine when formulated with just Al(OH) 3 . Adding …

Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies

…, AR Noe, L Shi, SW Tse, P Sinnis… - The Journal of …, 2015 - academic.oup.com
falciparum CSP, and this protection is greatly enhanced when combined with antirepeat …
in vivo protective activity and indicate that pre-erythrocytic vaccines against Plasmodium should …

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

N Klonis, MP Crespo-Ortiz, I Bottova… - Proceedings of the …, 2011 - National Acad Sciences
falciparum is protected against oxidative damage by thioredoxin- and glutathione-based
redox systems (34). However the parasite does not encode catalase or a classical glutathione …

In vitro and in vivo studies on protective and inhibitory antibodies against Plasmodium falciparum in the Saimiri monkey.

T Fandeur, P Dubois, J Gysin, JP Dedet… - Journal of immunology …, 1984 - journals.aai.org
… Plasmodium falciparum and with differing … Their protective activity was assessed in studies
of passive transfer of immunity in vivo, and their neutralizing activity was measured in studies …

[HTML][HTML] Chemoprotective antimalarial activity of P218 against Plasmodium falciparum: a randomized, placebo-controlled volunteer infection study

MF Chughlay, M El Gaaloul, C Donini… - The American Journal …, 2021 - ncbi.nlm.nih.gov
… By day 28, all participants in cohort 2 (P218 1,000 mg) and 8/9 in cohort 3 (P218 100 mg)
were sterilely protected post-PfSPZ VIS, confirming P218 P. falciparum chemoprotective activity

Age-dependent characteristics of protection v. susceptibility to Plasmodium falciparum

JK Baird - 1998 - digitalcommons.unl.edu
… The multifactorial and multistage character of protective immunity to Plasmodium
falciparum, naturally acquired by an indigenous population in Burkina Faso. Scandinavian …

Inhibition of entry of Plasmodium falciparum and P. vivax sporozoites into cultured cells; an in vitro assay of protective antibodies.

MR Hollingdale, EH Nardin, S Tharavanij… - … (Baltimore, Md.: 1950 …, 1984 - journals.aai.org
protected against sporozoite-induced P.falciparum malaria after immunization, completely
inhibited P.… The detection of naturally acquired antibodies with protective anti-invasive activity