U Certa, P Ghersa, H Döbeli, H Matile, HP Kocher… - Science, 1988 - science.org
… Plasmodiumfalciparum induces immunity to malaria in monkeys. However, antigenic polymorphism and repetitive amino acids commonly found in protective … showed aldolase activity. …
… falciparum. We obtained crystal structures of the Fab fragments for five of these antibodies … -parasite activity by conducting an in vivo protection study in mice using transgenic P. berghei …
… Its partial protective efficacy and low or non-protectiveactivity in the newborn led to us deciding to halt further clinical trials with this vaccine when formulated with just Al(OH) 3 . Adding …
…, AR Noe, L Shi, SW Tse, P Sinnis… - The Journal of …, 2015 - academic.oup.com
… falciparum CSP, and this protection is greatly enhanced when combined with antirepeat … in vivo protectiveactivity and indicate that pre-erythrocytic vaccines against Plasmodium should …
N Klonis, MP Crespo-Ortiz, I Bottova… - Proceedings of the …, 2011 - National Acad Sciences
… falciparum is protected against oxidative damage by thioredoxin- and glutathione-based redox systems (34). However the parasite does not encode catalase or a classical glutathione …
T Fandeur, P Dubois, J Gysin, JP Dedet… - Journal of immunology …, 1984 - journals.aai.org
… Plasmodium falciparum and with differing … Their protectiveactivity was assessed in studies of passive transfer of immunity in vivo, and their neutralizing activity was measured in studies …
MF Chughlay, M El Gaaloul, C Donini… - The American Journal …, 2021 - ncbi.nlm.nih.gov
… By day 28, all participants in cohort 2 (P218 1,000 mg) and 8/9 in cohort 3 (P218 100 mg) were sterilely protected post-PfSPZ VIS, confirming P218 P. falciparum chemoprotective activity…
… The multifactorial and multistage character of protective immunity to Plasmodium falciparum, naturally acquired by an indigenous population in Burkina Faso. Scandinavian …
… protected against sporozoite-induced P.falciparum malaria after immunization, completely inhibited P.… The detection of naturally acquired antibodies with protective anti-invasive activity …