[HTML][HTML] Potently neutralizing and protective human antibodies against SARS-CoV-2

SJ Zost, P Gilchuk, JB Case, E Binshtein, RE Chen… - Nature, 2020 - nature.com
… The human antibodies studied in this paper were isolated from blood samples from two
individuals in North America with previous laboratory-confirmed symptomatic SARS-CoV-2 …

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

MA Tortorici, M Beltramello, FA Lempp, D Pinto… - Science, 2020 - science.org
… To evaluate the protective efficacy of S2E12 and S2M11 against SARS-CoV-2 challenge
in vivo, we tested either mAb or a cocktail of both mAbs in a Syrian hamster model (44). The …

[HTML][HTML] Humoral immune responses and neutralizing antibodies against SARS-CoV-2; implications in pathogenesis and protective immunity

J Carrillo, N Izquierdo-Useros, C Ávila-Nieto… - Biochemical and …, 2021 - Elsevier
… species when administered before virus exposure; therefore, … clinical use as recombinant
monoclonal antibodies (mAbs) is being … of antibodies against SASR-CoV-2 and their protective

[HTML][HTML] Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein

N Suryadevara, S Shrihari, P Gilchuk, LA VanBlargan… - Cell, 2021 - cell.com
… -2 recognize the spike (S) protein receptor-binding domain and block virus … of human
mAbs binding to diverse epitopes on the N-terminal domain (NTD) of S protein from SARS-CoV-2 …

[HTML][HTML] What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2?

M Hellerstein - Vaccine: X, 2020 - Elsevier
… of T-cell responses and resulting protective immunity. It would be a public … antibody response,
after SARS-CoV-2 natural infection and vaccines may prove critically valuable if protective

[HTML][HTML] Protective roles and protective mechanisms of neutralizing antibodies against SARS-CoV-2 infection and their potential clinical implications

EC Abebe, TA Dejenie - Frontiers in Immunology, 2023 - frontiersin.org
… -2, vaccine effectiveness, and duration of the humoral protective response, as well as
aiding … discusses the protective functions, possible protective mechanisms against SARS-CoV-2, …

[HTML][HTML] Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection

EM Anderson, EC Goodwin, A Verma, CP Arevalo… - Cell, 2021 - cell.com
… Identification of SARS-CoV-2-reactive antibodies in human sera collected prior to the COVID…
pre-pandemic SARS-CoV-2-reactive IgG antibodies in 431 human serum samples collected …

[HTML][HTML] Correlates of protection against SARS-CoV-2 in rhesus macaques

K McMahan, J Yu, NB Mercado, C Loos, LH Tostanoski… - Nature, 2021 - nature.com
antibody responses correlated with protectiveantibodies can protect against challenge
with SARS-CoV-2 in macaques 15,16 . In the present study, we show that polyclonal antibodies

[HTML][HTML] A potent and protective human neutralizing antibody against SARS-CoV-2 variants

S Shan, CK Mok, S Zhang, J Lan, J Li, Z Yang… - Frontiers in …, 2021 - frontiersin.org
antibodies may contribute to the residual serum neutralizing activity against SARS-CoV-2 …
a broad, potent, and protective antibody, P36-5D2, isolated from a SARS-CoV-2 convalescent …

A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection

P Zhou, M Yuan, G Song, N Beutler… - Science translational …, 2022 - science.org
… on β-CoV spike proteins for protective antibodies that … SARS-CoV-2 spike protein stem helix
antibody, CC40.8, for binding to and neutralization of diverse sarbecoviruses and SARS-CoV