A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease

R Haque, CM Watson, J Liu, EK Carter… - Science translational …, 2023 - science.org
… On the basis of our prior work integrating cerebrospinal fluid (CSF) and brain proteome …
targets 48 key proteins altered in CSF. To test the diagnostic utility of these proteins and compare …

Cerebrospinal fluid analysis

G Giovannoni - Handbook of clinical neurology, 2014 - Elsevier
… identified in concentrated cerebrospinal fluid and their relationship to serum proteins. Case
… of the protein components in cerebrospinal fluid and their relationship to the serum proteins, …

Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease

AH Simonsen, J McGuire, VN Podust, H Davies… - Neurobiology of …, 2008 - Elsevier
… Levels of these proteins in cerebrospinal fluid (CSF) are used routinely in parts of Europe
for research and diagnostic purposes; however, the diagnostic performance of these …

A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease

O Carrette, I Demalte, A Scherl… - PROTEOMICS …, 2003 - Wiley Online Library
… have been reported in the cerebrospinal fluid (CSF) of AD patients, in particular altered levels
of the tau protein and the 1-42 fragment of the amyloid precursor protein. These, however, …

Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment

AH Simonsen, J McGuire, O Hansson… - Archives of …, 2007 - jamanetwork.com
… unique panel of proteins in … panel of potential biomarkers found in this study needs to be
confirmed in larger cohorts of clinical samples to establish their true diagnostic value. This panel

… both systemic inflammation and neuroinflammation in fibromyalgia patients, as assessed by a multiplex protein panel applied to the cerebrospinal fluid and to plasma

E Bäckryd, L Tanum, AL Lind, A Larsson… - Journal of pain …, 2017 - Taylor & Francis
… However, concerning FM, previous human plasma/serum and/or cerebrospinal fluid (CSF) …
multiplex protein panel enabling simultaneous analysis of 92 inflammation-related proteins. …

Recommendations for cerebrospinal fluid analysis

D Hepnar, P Adam, H Žáková, M Krušina, P Kalvach… - Folia microbiologica, 2019 - Springer
… overview of available cerebrospinal fluid assays, shortened … and inevitable basic routine
panel, and following complicated … proteins, assessment of the so-called CSF triplet (tau-protein, …

A multiplex protein panel applied to cerebrospinal fluid reveals three new biomarker candidates in ALS but none in neuropathic pain patients

AL Lind, D Wu, E Freyhult, C Bodolea, T Ekegren… - PLoS …, 2016 - journals.plos.org
… Measurements of proteins in cerebrospinal fluid (CSF) … However, adequate tools for parallel
and sensitive protein … We designed a novel multiplex SP-PLA (S1 Fig) protein panel for …

A panel of nine cerebrospinal fluid biomarkers may identify patients with atypical parkinsonian syndromes

NK Magdalinou, RW Paterson, JM Schott… - Journal of Neurology …, 2015 - jnnp.bmj.com
… Objective To use a panel of cerebrospinal fluid (CSF) biomarkers to differentiate patients …
amyloid precursor protein soluble metabolites α and β (soluble amyloid precursor protein (sAPP…

Clinical proteomics of the cerebrospinal fluid: towards the discovery of new biomarkers

S Roche, A Gabelle, S Lehmann - PROTEOMICS–Clinical …, 2008 - Wiley Online Library
… The cerebrospinal fluid (CSF) circulates within the CNS … This biological fluid has an important
protein diversity that results … These panels of depleted proteins could be obtained using …