[HTML][HTML] Peptide and peptide-based inhibitors of SARS-CoV-2 entry

D Schütz, YB Ruiz-Blanco, J Münch, F Kirchhoff… - Advanced drug delivery …, 2020 - Elsevier
… of peptides inhibiting SARS-CoV-2 entry and outline the strategies used to design peptides
… The high similarity between the S proteins of SARS-CoV-1 and SARS-CoV-2 suggests that …

Amyloidogenesis of SARS-CoV-2 spike protein

S Nystrom, P Hammarstrom - Journal of the American Chemical …, 2022 - ACS Publications
… Encouraged by the results, we generated 20-AA peptides from the full-length SARS-CoV-2
S-protein. We aimed to address the most amyloidogenic sequences and used the WALTZ (…

Antiviral peptides as promising therapeutics against SARS-CoV-2

SM Chowdhury, SA Talukder, AM Khan… - The Journal of …, 2020 - ACS Publications
… of the test peptides with the RBD of the SARS CoV-2 spike protein. Subsequently, PCA was
performed taking the five most important peptide properties to cluster the test peptides in a …

Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides

BJ Bosch, BEE Martina… - Proceedings of the …, 2004 - National Acad Sciences
… We have previously shown that the HR1 and HR2 peptides of the MHV spike protein, when
… that the HR1 and HR2 peptides of the SARS-CoV spike protein behave in a similar manner. …

[HTML][HTML] In silico design of antiviral peptides targeting the spike protein of SARS-CoV-2

R Ling, Y Dai, B Huang, W Huang, J Yu, X Lu, Y Jiang - Peptides, 2020 - Elsevier
… S protein and S1 subunit between SARS and SARS-CoV-2 indicates the high evolution of
beta-coronavirus, … We will further simulate the antivirus peptide with modification and test the …

Evidence supporting the use of peptides and peptidomimetics as potential SARS-CoV-2 (COVID-19) therapeutics

S VanPatten, M He, A Altiti, KF Cheng… - Future medicinal …, 2020 - Taylor & Francis
… -based therapeutics that have been described for SARS-CoV-2 and SARS-CoV, which
target the S protein–ACE2 interaction and entry process. Some of these are modified …

Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides

S Pomplun - RSC Medicinal Chemistry, 2021 - pubs.rsc.org
… designed miniproteins and peptides. This review article outlines … peptides, targeting the
SARS-CoV-2-spike protein (Table 1). … affinity for the SARS-CoV-2-spike protein and the discovery …

[HTML][HTML] On the molecular determinants of the SARS-CoV-2 attack

D Kanduc, Y Shoenfeld - Clinical Immunology (Orlando, Fla.), 2020 - ncbi.nlm.nih.gov
… commonalities between the pathogen and the human proteins might trigger cross-reactions …
SARS-CoV-2 and HCoV-229E for peptide sharing with human surfactant and related proteins

[HTML][HTML] De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2

X Huang, R Pearce, Y Zhang - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
… RBD than the peptides composed of residues 22-44 or 22-… SARS-CoV RBD/hACE2 and
SARS-CoV-2 RBD/hACE2, we hypothesize that this artificial peptide may also bind to SARS-CoV

Inhibition of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) infectivity by peptides analogous to the viral spike protein

B Sainz Jr, EC Mossel, WR Gallaher, WC Wimley… - Virus research, 2006 - Elsevier
… of SARS-CoV entry in vitro, development of other peptide fusion inhibitors, based on non-HR
regions of the viral fusion protein, … to identify new peptide inhibitors of SARS-CoV. Using the …