Tissue-based proteomic profiling in patients with hyperplasia and endometrial cancer

K Akkour, IO Alanazi, AA Alfadda, H Alhalal, A Masood… - Cells, 2022 - mdpi.com
… used tissue-based proteomic profiling analysis in patients with endometrial cancer and
hyperplasia, and control patients. … Thirty-six patients (twelve with endometrial cancer, twelve with …

Proteomics-based signature for human benign prostate hyperplasia and prostate adenocarcinoma

AA Alaiya, M Al-Mohanna… - International …, 2011 - spandidos-publications.com
… This study aimed to identify and validate proteomics-based biomarkers useful for … hyperplasia
(BPH). Global protein expression patterns in fresh tissue specimens from 8 patients with …

Tissue proteome signatures associated with five grades of prostate cancer and benign prostatic hyperplasia

R Kawahara, S Recuero, FCS Nogueira… - …, 2019 - Wiley Online Library
proteome profiling.24 The intensity of different peptides from the same protein can vary
greatly, impacting the accuracy of the protein abundance measurement. Moreover, the sensitivity …

Prohibitin identified by proteomic analysis of prostate biopsies distinguishes hyperplasia and cancer

R Ummanni, H Junker, U Zimmermann, S Venz… - Cancer Letters, 2008 - Elsevier
… from benign prostate hyperplasia (BPH, n = 11) and prostate cancer (PCA, n = 12) patients by
two… 2-DE results revealed 88 protein spots expressed differentially among hyperplasia and …

Plasma-based proteomic profiling identifies the distinct regulation of proteins in hyperplasia and endometrial cancer

K Akkour, IO Alanazi, AA Alfadda, A Masood, H Alhalal… - BMC cancer, 2024 - Springer
… This study explored the proteomic profiles of plasma samples obtained from EC patients,
those with hyperplasia (Hy), and a control group (CO). A combination of techniques, such as 2D…

Identification of potential complementary serum biomarkers to differentiate prostate cancer from benign prostatic hyperplasia using gel‐and lectin‐based proteomics …

JJ Jayapalan, KL Ng, AHA Razack… - Electrophoresis, 2012 - Wiley Online Library
… In the present study, we have profiled the sera of patients with PCa and benign prostatic
hyperplasia (BPH) using the gel- and lectin-based proteomics methods and demonstrated the …

Proteomic analysis of patient tissue reveals PSA protein in the stroma of benign prostatic hyperplasia

KJ O'Malley, K Eisermann, LE Pascal… - The …, 2014 - Wiley Online Library
… In the current study, proteomics analyses were utilized to identify proteins altered in the BPH
stromal compartment from patients with symptomatic BPH. Stromal cells were isolated from …

Development of a predictive model to distinguish prostate cancer from benign prostatic hyperplasia by integrating serum glycoproteomics and clinical variables

C Gabriele, F Aracri, LE Prestagiacomo, MA Rota… - Clinical Proteomics, 2023 - Springer
… model able to discriminate between PCa and BPH patients based on a combination of
clinical and proteomic variables. Proteomic data were generated by a multistage biomarker …

Comparative Serum Proteome Profiling of Canine Benign Prostatic Hyperplasia before and after Castration

S Ploypetch, G Wongbandue, S Roytrakul… - Animals, 2023 - mdpi.com
… the serum proteome of dogs with BPH. This study aimed to compare serum proteome profiles
of … This research represents the first investigation into serum proteome profiling in dogs with …

Human periprostatic adipose tissue: Secretome from patients with prostate cancer or benign prostate hyperplasia

PA Sacca, ON Mazza, C Scorticati… - … & Proteomics, 2019 - cgp.iiarjournals.org
… prostate hyperplasia (BPH) patients. Patients and Methods: Liquid chromatography-mass
spectrometry-based proteomic analysis was performed in PPAT-conditioned media (CM) from …