More effective purifying selection on RNA viruses than in DNA viruses

AL Hughes, MAK Hughes - Gene, 2007 - Elsevier
… of purifying selection in RNA viruses than in DNA viruses, implying that purifying selection
has been … of slightly deleterious nonsynonymous variants in RNA viruses than in DNA viruses. …

Biased mutation and selection in RNA viruses

T Kustin, A Stern - Molecular Biology and Evolution, 2021 - academic.oup.com
… or by biased mutation processes, we harnessed the effects of incomplete purifying selection
at the tips of virus phylogenies. Our results revealed consistent mutational biases toward U …

Evolution of sex in RNA viruses

L Chao - Trends in ecology & evolution, 1992 - cell.com
… by a mutation-selection … A second confirmation of purifying selection in RNA viruses comes
from molecular … Purifying selection can explain why some RNA viruses are segmented and …

Selection pressures in the capsid genes of plant RNA viruses reflect mode of transmission

ER Chare, EC Holmes - Journal of General Virology, 2004 - microbiologyresearch.org
… This analysis provided strong evidence that the capsid proteins of vector-borne plant
viruses are subject to greater purifying selection on amino acid change than those …

Patterns of intra-and interhost nonsynonymous variation reveal strong purifying selection in dengue virus

EC Holmes - Journal of virology, 2003 - Am Soc Microbiol
selection pressures acting on arthropod-borne RNA viruses (arboviruses). In particular, it is
unclear why arboviruses such as dengue virus … in populations of dengue virus sampled at …

Purifying selection can obscure the ancient age of viral lineages

JO Wertheim… - Molecular biology and …, 2011 - academic.oup.com
… to the problem of underestimated branch lengths due to purifying selection, our results do
point to a couple of guidelines when inferring tMRCAs in RNA viruses. First, the inference of …

Are RNA viruses adapting or merely changing?

M Sala, S Wain-Hobson - Journal of molecular evolution, 2000 - Springer
RNA viruses and retroviruses fix substitutions approximately 1 million-fold faster than their
hosts. This diversification could represent an inevitable drift under purifying selection, the …

The evolution of RNA viruses: a population genetics view

A Moya, SF Elena, A Bracho… - Proceedings of the …, 2000 - National Acad Sciences
… Following those authors, population genetics theory is a good descriptor for those populations
where mutations are rare events and purifying selection is the main evolutionary force …

Reduced positive selection in vector-borne RNA viruses

CH Woelk, EC Holmes - Molecular biology and evolution, 2002 - academic.oup.com
… (VSV) and analyzed rates of mutation in the short-term, which may have included deleterious
changes that are removed by purifying selection at transmission. A similar pattern has been …

Recombination and selection in the evolution of picornaviruses and other mammalian positive-stranded RNA viruses

P Simmonds - Journal of virology, 2006 - Am Soc Microbiol
… picornavirus serotypes, in which neutral or purifying selection was prominent. Overall, this
… -stranded RNA virus family Picornaviridae comprises a diverse range of mammalian viruses