… molecule taken from structural database (PDB). In-Silico drug designing approaches follow
for molecular docking studies … , we got 5 best derivatives of pyrazolopyrimidine with optimal …

… In this study, new pyrazolopyrimidine derivatives were designed and evaluated for
anticancer activity. PIM-1 … Molecular docking study and molecular dynamics were also done. …

… pyrazolopyrimidines as pyrazoloquinazoline and benzoimidazo pyrazolopyrimidine derivatives
… [ 29, 30 ] The anticancer evaluation and the molecular docking using COX-2 enzyme of …

… -QSAR) studies on novel class of pyrazolopyrimidine derivatives as GSK-3 inhibitors reported
to have improved cellular activity. Docked conformation of the most active molecule in the …

… cytotoxic properties; the most potent derivative 7, had an IC … protein's crystal structure for
KDM5A was docked with the newly created aminopyrazole and pyrazolopyrimidine derivatives …

… was utilized for the production of new functionalized pyrazolopyrimidine … Molecular docking
of the prepared pyrazolopyrimidines 4 and 6 with the crystal structure of the KDM5A protein, …

… Molecular docking studies indicated the binding mode of [1,2,4]triazolo[1,5-a]pyrimidine
derivatives to PfDHODH, and the highest interaction affinities for the PfDHODH enzyme were in …

… Bicyclic pyrazolopyrimidine derivatives dramatically increase the biological … studies, and
biological properties of pyrazolopyrimidine, the synthesis of some novel pyrazolopyrimidine is …

… Based on the aforementioned studies and the substantial … synthesis of novel pyrazolopyrimidine
derivatives as COXs and … pyrazolopyrimidine system to various piperazine derivatives or …

… Finally, the molecular docking studies performed inside the … Furthermore, pyrazolopyrimidine
14d and the pyrazole Schiff … Both the pyrazolopyrimidine derivatives (14c and 14g–i) and …