… and imdevimab antibody combination vs placebo on development of symptomatic COVID-19 in early asymptomatic SARS-CoV-2 infection: a randomized clinical trial

MP O'Brien, E Forleo-Neto, N Sarkar, F Isa, P Hou… - Jama, 2022 - jamanetwork.com
… A 2-part, phase 3 randomized clinical trial among asymptomatic household contacts of …
antibody), would prevent infection and/or COVID-19 in this high-risk setting. In Part A of the trial, …

… live births in patients with recurrent pregnancy loss and positive anti-phospholipid antibodies: a meta-analysis of randomized controlled trials and meta-regression

A Mak, MWL Cheung, AA Cheak, RC Ho - Rheumatology, 2010 - academic.oup.com
… In the first stage, we excluded clinical trials not apparently comparing the combination of
aspirin and heparin and aspirin alone (n = 9), irrelevant trials (n = 15), non-RCTs (n = 2) and five …

[HTML][HTML] Subcutaneous REGEN-COV antibody combination in early asymptomatic SARS-Cov-2 infection: a randomized clinical trial

…, COVID-19 Phase 3 Prevention Trial Team - MedRxiv, 2021 - ncbi.nlm.nih.gov
… The two-antibody combination reduces the risk of … We conducted a phase 3, randomized
controlled trial in … 1200 mg (600 mg of each monoclonal antibody) may prevent infection and/or …

… efficacy of casirivimab and imdevimab COVID-19 antibody combination in outpatients with SARS-CoV-2 infection: a phase 2 dose-ranging randomized clinical trial

C Portal-Celhay, E Forleo-Neto, W Eagan… - JAMA Network …, 2022 - jamanetwork.com
… Prevention Trial Team. Effect of subcutaneous casirivimab and imdevimab antibody combination
vs … COVID-19 in early asymptomatic SARS-CoV-2 infection: a randomized clinical trial.  …

Effect of bamlanivimab as monotherapy or in combination with etesevimab on viral load in patients with mild to moderate COVID-19: a randomized clinical trial

RL Gottlieb, A Nirula, P Chen, J Boscia, B Heller… - Jama, 2021 - jamanetwork.com
Combining these 2 neutralizing monoclonal antibodies in clinical use may enhance viral load
… Third, only 1 combination dose was chosen for this study. Because the antiviral activity of …

Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial

B Julg, KE Stephenson, K Wagh, SC Tan, R Zash… - Nature medicine, 2022 - nature.com
… 1 and (3 + 3 mg kg −1 , 10 + 10 mg kg −1 or 30 + 30 mg kg −1 ) in group 2 were randomized
at a ratio of three antibody recipients to one placebo recipient, respectively (total of nine …

… combined with cetuximab or bevacizumab on overall survival in patients with KRAS wild-type advanced or metastatic colorectal cancer: a randomized clinical trial

AP Venook, D Niedzwiecki, HJ Lenz, F Innocenti… - Jama, 2017 - jamanetwork.com
… These new options for patients with advanced or metastatic colorectal cancer raised the
question of which was the optimal biologic monoclonal antibody-chemotherapy combination. …

Double‐blind randomized controlled clinical trial of the interleukin‐6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an …

RN Maini, PC Taylor, J Szechinski… - Arthritis & …, 2006 - Wiley Online Library
… Following stabilization, they were randomized to 1 of 7 … monotherapy or in combination
with MTX, or MTX plus placebo. … antibodies developed against this murine antibody (30). …

[HTML][HTML] … of chronic antibody mediated rejection with intravenous immunoglobulins and rituximab: a multicenter, prospective, randomized, double-blind clinical trial

F Moreso, M Crespo, JC Ruiz, A Torres… - American Journal of …, 2018 - Elsevier
… However, to the best of our knowledge no trials to test the efficacy and … , randomized,
placebo-controlled, double-blind clinical trial to evaluate the efficacy and safety of IVIG combined

A randomized, controlled trial to evaluate the effect of an anti-interleukin-9 monoclonal antibody in adults with uncontrolled asthma

CK Oh, R Leigh, KK McLaurin, K Kim, M Hultquist… - … research, 2013 - Springer
Background Preclinical studies suggest that interleukin-9 may be a central mediator in the
development and maintenance of airway inflammation in asthma. The aim of this study was …