Randomized trial of molnupiravir or placebo in patients hospitalized with Covid-19

JR Arribas, S Bhagani, SM Lobo, I Khaertynova… - NEJM …, 2022 - evidence.nejm.org
… of molnupiravir seen in preclinical studies and a phase 1 trial … The potential of molnupiravir
as an antiviral treatment for … phase 2/3 studies, one in outpatients (MOVe-OUT trial 9 , 10 ) …

Molnupiravir for the treatment of non-severe COVID-19: a systematic review and meta-analysis of 14 randomized trials with 34 570 patients

M Sun, H Lai, J Huang, J Liu, Y Li, J Tian… - Journal of …, 2023 - academic.oup.com
… review and meta-analysis of randomized controlled trials that allocated adult patients with
non-severe COVID-19 to molnupiravir or a control. We used random-effects models, and …

Efficacy and safety of molnupiravir treatment for COVID-19: a systematic review and meta-analysis of randomized controlled trials

F Tian, Q Feng, Z Chen - International Journal of Antimicrobial Agents, 2023 - Elsevier
… The Cochrane risk of bias tool for randomised trials was used to assess … randomised clinical
studies were included for a full evaluation of the efficacy and safety of molnupiravir treatment

Effect of molnupiravir on biomarkers, respiratory interventions, and medical services in COVID-19: a randomized, placebo-controlled trial

MG Johnson, A Puenpatom, PA Moncada… - Annals of internal …, 2022 - acpjournals.org
… of all randomly assigned participants, molnupiravir showed a … potential benefits of molnupiravir
for the treatment of mild to … all randomly assigned participants who received molnupiravir

… alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

CC Butler, FDR Hobbs, OA Gbinigie, NM Rahman… - The Lancet, 2023 - thelancet.com
Trials of molnupiravir have previously been done in largely unvaccinated participants …
Our trial provides an estimate of the effectiveness of molnupiravir in a multiply vaccinated …

Molnupiravir for treatment of adults with mild or moderate COVID-19: a systematic review and meta-analysis of randomized controlled trials

Y Gao, M Liu, Z Li, J Xu, J Zhang, J Tian - Clinical Microbiology and …, 2023 - Elsevier
… The effects of molnupiravir in treating patients with non-… In adult patients with mild or moderate
COVID-19, molnupiravirMolnupiravir probably increases the rate of viral clearance (RR, …

Molnupiravir for oral treatment of Covid-19 in nonhospitalized patients

A Jayk Bernal, MM Gomes da Silva… - … England Journal of …, 2022 - Mass Medical Soc
… -blind, randomized, placebo-controlled trial to evaluate the efficacy and safety of treatment
with molnupiravir started … Participants in the trial were randomly assigned to receive 800 mg of …

Efficacy and safety of molnupiravir for the treatment of SARS-CoV-2 infection: a systematic review and meta-analysis

JJ Malin, S Weibel, H Gruell… - Journal of …, 2023 - academic.oup.com
… of molnupiravir for COVID-19 treatment in … trial indicated no reduction in the low rates for
hospitalization or death among vaccinated outpatients with risk factors treated with molnupiravir. …

Antiviral efficacy and safety of molnupiravir against omicron variant infection: a randomized controlled clinical trial

R Zou, L Peng, D Shu, L Zhao, J Lan, G Tan… - Frontiers in …, 2022 - frontiersin.org
study, we performed a randomized, controlled study to evaluate the clinical efficacy of
molnupiravir … In our study, we found that molnupiravir was effective in treating COVID-19 caused …

… efficacy and safety of molnupiravir for nonhospitalized and hospitalized patients with COVID‐19: a systematic review and meta‐analysis of randomized control trials

PY Huang, TH Liu, JY Wu, YW Tsai… - Journal of Medical …, 2023 - Wiley Online Library
… conducted to assess the clinical efficacy of molnupiravir in treating patients with COVID-19. …
In the present study, molnupiravir was effective in reducing the risks of mortality and …