Rational use of tocilizumab in the treatment of novel coronavirus pneumonia

S Zhang, L Li, A Shen, Y Chen, Z Qi - Clinical drug investigation, 2020 - Springer
… [33] summarized a number of literatures on tocilizumab treatment of Takayasu arteritis and
found that its use could reduce (or even stop) the dosage of glucocorticoids. Samson et al. [34…

Rational use of tocilizumab in COVID-19

S Jain, SK Sharma - Annals of the rheumatic diseases, 2022 - ard.bmj.com
… patients treated with tocilizumab.8 Candidaemia with candidal endophthalmitis and endocarditis
was reported in 3 of the 43 severe COVID-19 patients treated with tocilizumab in Italy.9 …

Response to:'Rational use of tocilizumab in COVID-19'by Jain and Sharma

N Potere, M Di Nisio, D Cibelli, R Scurti… - Annals of the …, 2022 - ard.bmj.com
… related to the treatment with tocilizumab, possibly causing an … early subcutaneous treatment
with tocilizumab are definitely … more that patients treated with subcutaneous tocilizumab for …

[HTML][HTML] Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

A Cortegiani, M Ippolito, M Greco, V Granone, A Protti… - Pulmonology, 2021 - Elsevier
… The aim of this systematic review was to describe the rationale for the use of tocilizumab
for the treatment of COVID-19 and to summarize the available evidence regarding its efficacy …

Targeting IL-6 in COVID-19. Response to:'Rational use of tocilizumab in COVID-19'by Jain and Sharma

PL Capecchi, PE Lazzerini - Annals of the Rheumatic Diseases, 2022 - ard.bmj.com
… perforation during tocilizumab treatment, the possible role of the concomitant treatment with
… Nevertheless, we acknowledge that data on the efficacy of tocilizumab are still preliminary …

Early use of low dose tocilizumab in patients with COVID-19: a retrospective cohort study with a complete follow-up

N De Rossi, C Scarpazza, C Filippini, C Cordioli… - …, 2020 - thelancet.com
… Regarding laboratory results, if one or more laboratory test resulted to statistically differ
between tocilizumab and standard treatment group with a potential clinical relevance, we were …

Therapeutic role of tocilizumab in SARS-CoV-2-induced cytokine storm: rationale and current evidence

C Pelaia, C Calabrese, E Garofalo, A Bruni… - International Journal of …, 2021 - mdpi.com
… Indeed, the IL-6-receptor antagonist tocilizumab, already approved for treatment of … So
far, the growing body of studies assessing the efficacy and safety of tocilizumab for treatment of …

Tocilizumab in SARS-CoV-2 patients with the syndrome of cytokine storm: A narrative review

S Kulanthaivel, VB Kaliberdenko… - Reviews on Recent …, 2021 - ingentaconnect.com
… The retrospective study included 15 patients who were treated with tocilizumab from Jan 27
… The rational use of the tocilizumab in severe and critically ill COVID-19 patients can prevent …

[HTML][HTML] Use of tocilizumab in COVID-19: a systematic review and meta-analysis of current evidence

S Kotak, M Khatri, M Malik, M Malik, W Hassan… - Cureus, 2020 - ncbi.nlm.nih.gov
… the efficacy of IL-6 blockers such as tocilizumab in treating critical COVID-19 patients [24-26].
Tocilizumab is approved by the FDA to treat rheumatoid arthritis, giant cell arteritis, poly-…

Association between early treatment with tocilizumab and mortality among critically ill patients with COVID-19

S Gupta, W Wang, SS Hayek, L Chan… - JAMA internal …, 2021 - jamanetwork.com
… study was lower in patients treated with tocilizumab in the first 2 days of ICU admission
compared with patients whose treatment did not include early use of tocilizumab. However, the …