[HTML][HTML] Rationale and evidence on the use of tocilizumab in COVID-19: a systematic review

A Cortegiani, M Ippolito, M Greco, V Granone, A Protti… - Pulmonology, 2021 - Elsevier
… for the treatment of severe COVID-19. The aim of this systematic review was to describe
the rationale for the use of tocilizumab for the treatment of COVID-19 and to summarize the …

COVID-19: coagulopathy, risk of thrombosis, and the rationale for anticoagulation

W Miesbach, M Makris - Clinical and applied thrombosis …, 2020 - journals.sagepub.com
… rates for SARS and MERS, COVID-19 has led to more deaths … , 6 a characteristic feature of
COVID-19 is that a proportion of … been described in patients with COVID-19, and this review …

Rationale for targeting complement in COVID19

A Polycarpou, M Howard, CA Farrar… - EMBO molecular …, 2020 - embopress.org
COVID-19 caused by SARS-CoV-2 is associated with an … The manifestations of severe
COVID-19 such as the ARDS, … MERS-CoV infection linking severe COVID-19 disease directly with …

[HTML][HTML] Rationale for the use of N‐acetylcysteine in both prevention and adjuvant therapy of COVID19

S De Flora, R Balansky, S La Maestra - The FASEB journal, 2020 - ncbi.nlm.nih.gov
… Approximately 15% of coronavirus disease‐2019 (COVID19… ARDS, the leading cause
of death in COVID19 patients, … Besides affecting the respiratory system, COVID19 affects …

The rationale for potential pharmacotherapy of COVID-19

M Saber-Ayad, MA Saleh, E Abu-Gharbieh - Pharmaceuticals, 2020 - mdpi.com
coronavirus (MERS-CoV) prompted the identification of compounds that could theoretically
be active against the emerging coronavirus … considerations in COVID-19 patients in order to …

Rationale for the clinical use of adipose-derived mesenchymal stem cells for COVID-19 patients

CJ Rogers, RJ Harman, BA Bunnell… - Journal of translational …, 2020 - Springer
… In January, a highly contagious novel coronavirus (now … safe and effective treatments for
COVID-19 patients because, … sector for the use of MSC therapies in COVID-19 patients. MSCs …

Rationale for azithromycin in COVID-19: an overview of existing evidence

I Gyselinck, W Janssens… - BMJ Open …, 2021 - bmjopenrespres.bmj.com
… or late stage molecules for COVID-19, parallel to the … adoption of azithromycin in routine
COVID-19 care, further fuelled … we comprehensively review the rationale of its use against SARS-…

Targeting GM-CSF in COVID-19 pneumonia: rationale and strategies

A Bonaventura, A Vecchié, TS Wang, E Lee… - Frontiers in …, 2020 - frontiersin.org
… in COVID-19 patients with the rationale that it may help clear the SARS-CoV-2 earlier in the
disease course. However, in the later phase of COVID-19 … the onset of COVID-19 pneumonia …

[HTML][HTML] Rationale for the use of sphingosine analogues in COVID-19 patients

DR Tasat, JS Yakisich - Clinical Medicine, 2021 - Elsevier
… Despite the recent announcement of promising drug candidates to treat COVID-19, there
is … for the severity of disease seen in COVID-19 patients. In support of this hypothesis, pilot …

Design and rationale of the COVID-19 Critical Care Consortium international, multicentre, observational study

GL Bassi, J Suen, AG Barnett, A Corley, J Millar… - BMJ open, 2020 - bmjopen.bmj.com
rationale and design of an international, multicentre, observational registry of patients with
COVID-19 … To date, the characterisation of patients admitted to ICUs with COVID-19 has been …