A model for reactivation of CMV from latency

M Hummel, MM Abecassis - Journal of Clinical Virology, 2002 - Elsevier
… The mechanism by which CMV reactivates from latency has not been well understood. …
models for reactivation from latency and present evidence in favor of the model that reactivation is …

Reactivation of VX-Inhibited Human Acetylcholinesterase by Deprotonated Pralidoxime. A Complementary Quantum Mechanical Study

JA Valle da Silva, AF Pereira, S Laplante, K Kuca… - Biomolecules, 2020 - espace.inrs.ca
reactivation through deprotonated 2-PAM is lower than for the protonated 2-PAM. This
corroborates our hypothesis that the reactivation mechanism … of the mechanism of reactivation of …

[HTML][HTML] Reactivation of hepatitis B after liver transplantation: Current knowledge, molecular mechanisms and implications in management

R Chauhan, S Lingala, C Gadiparthi… - World journal of …, 2018 - ncbi.nlm.nih.gov
… However, there are several other molecular mechanisms through which HBV may reactivate
… post-LT HBV reactivation, its risk factors, underlying molecular mechanisms, and recent …

Oxime-mediated in vitro reactivation kinetic analysis of organophosphates-inhibited human and electric eel acetylcholinesterase

AK Sahu, R Sharma, B Gupta, K Musilek… - … Mechanisms and …, 2016 - Taylor & Francis
… interrupt the catalytic mechanism of acetylcholinesterase (… be reactivated by the nucleophilic
action of oxime reactivators. To analyze the effect of different AChE sources on reactivation

Reactivation mechanism of a large-scale ancient landslide

C Zhang, Y Yin, Z Dai, B Huang, Z Zhang, X Jiang… - Landslides, 2021 - Springer
reactivated landslide in Wushan Town, Chongqing, China. The landslide was reactivated
the landslide deformation characteristics and reactivation mechanism. The results show that …

Refinement of structural leads for centrally acting oxime reactivators of phosphylated cholinesterases

Z Radić, RK Sit, Z Kovarik, S Berend, E Garcia… - Journal of Biological …, 2012 - ASBMB
… To distinguish whether molecular recognition or intrinsic chemical reactivity of RS41A was
dominant in influencing overall reactivation potency, we analyzed reactivation kinetics of …

A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2′-dC upon inhibition of ribonucleotide …

A Minkovsky, A Sahakyan, G Bonora… - Epigenetics & …, 2015 - Springer
… Here, we screened for siRNAs and chemicals that reactivate an Xi-linked reporter in the …
methyltransferase 1, at a concentration that, on its own, is not sufficient for Xi-reactivation. …

Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose

TM Shih, JW Skovira, JC O'Donnell… - … mechanisms and …, 2009 - Taylor & Francis
Reactivation occurs through nucleophilic attack by the oxime on the phosphorous atom…
reactivating action of the oximes is considered to be the major mechanism of their antidotal action

The relationship between oxime-induced reactivation of carbamylated acetylcholinesterase and antidotal efficacy against carbamate intoxication

LW Harris, BG Talbot, WJ Lennox… - Toxicology and applied …, 1989 - Elsevier
… when HI-6 was combined with atropine therapy, the PR was further elevated to 23.3. The
data in Table 3 show that the LD50 values for carbaryl and for atropine plus carbaryl were less (…

Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer …

Y Li, YY Yuan, SM Meeran, TO Tollefsbol - Molecular cancer, 2010 - Springer
mechanisms of ERα-reactivation and to explore the applicability of this or similar combination
to breast … We found, for the first time, that EGCG and TSA can synergistically reactivate ERα …