… Because receptor binding also … affinity for the viral receptor compared with the spike of
XBB.1.5 or EG.5.1 (Figs. 4a,b). In fact, BA.2.86 spike has one of the highest receptor affinities we …

… We measured the binding affinities between each of the three RBDs (SARS-CoV-2, … ,
we characterized ACE2-binding affinities of the SARS-CoV-2 spike that contains mutations in …

… SARS-CoV-2 binding affinity caused by these residue mutations. This research identified
the binding affinity differences of the SARS-CoV-… wild-type SARS-CoV-2 spike receptor-binding …

… affinity for the hACE2 receptor, we purified the hACE2 ectodomain and different SARS-CoV-2
RBD variants from human cells (Figure S2(A)–(D)), and determined rate and affinity …

… -2 variant RBDs and hACE2, we measured their binding affinity using surface plasmon
resonance (SPR). Mouse Fc (mFc) tagged hACE2 was captured in a CM5 chip that pre-…

… affinities of the S proteins of SARS-CoV and SARS-CoV-2 to the ACE2. Our results show
that the protein surface of the ACE2 at the receptor … the S proteins of SARS-CoV/SARS-CoV-2. …

… Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved variants with
substitutions in the spike receptor-binding domain (RBD) that affect its affinity for angiotensin-…

… Here we perform a detailed affinity and kinetics analysis of the … SARS-CoV-2 Alpha (B.1.1.7),
Beta (B.1.351), and Gamma (P1) variants. Most of these mutations increased the affinity of …

… have a much higher affinity for CoV-2 spike RBD compared to CoV spike RBD. Here we
examine the molecular basis underlying the different binding affinities of CoV and CoV-2 spike …

… However, we and others have shown that WT ACE2 binds the SARS-CoV-2 spike RBD
with only modest affinity ( K D ∼ 15 nM) (15–17). ACE2 is therefore a good candidate for …